Fluid responsiveness predicted by transcutaneous partial pressure of oxygen in patients with circulatory failure: a prospective study

Xu, Jingyuan; Peng, Xiao; Pan, Chun; Cai, Shixia; Zhang, Xiwen; Xue, Ming; Yang, Yi; Qiu, Haibo

doi:10.1186/s13613-017-0279-0

Annals of Intensive Care

Table 2 Hemodynamic variable at different phases in responders and non-responders during the study (n = 34)

From: Fluid responsiveness predicted by transcutaneous partial pressure of oxygen in patients with circulatory failure: a prospective study

Hemodynamic variable	Category	Before PLR	During PLR	Before volume expansion	After volume expansion
Heart rate (mean ± SD, beats/min)	Responder	99 ± 25	95 ± 23^a	98 ± 25	93 ± 23^b
Heart rate (mean ± SD, beats/min)	Non-responder	98 ± 24	100 ± 23	98 ± 24	97 ± 23
Mean arterial pressure (mean ± SD, mmHg)	Responder	66 ± 10	78 ± 8^a	67 ± 10	77 ± 8^b
Mean arterial pressure (mean ± SD, mmHg)	Non-responder	83 ± 13^c	87 ± 13^a	83 ± 12^c	85 ± 12^b
Central venous pressure (mean ± SD, mmHg)	Responder	8 ± 4	11 ± 5^a	9 ± 4	11 ± 5^b
Central venous pressure (mean ± SD, mmHg)	Non-responder	9 ± 4	11 ± 5^a	9 ± 4	11 ± 4^b
Cardiac output (mean ± SD, L/min)	Responder	5.5 ± 2.6	6.5 ± 2.9^a	5.6 ± 2.5	6.5 ± 3.0^b
Cardiac output (mean ± SD, L/min)	Non-responder	6.0 ± 2.3	6.1 ± 2.4	5.8 ± 2.3	6.0 ± 2.4^b
Cardiac index (mean ± SD, l/min m²)	Responder	3.4 ± 1.4	4.0 ± 1.5^a	3.4 ± 1.3	4.0 ± 1.6^b
Cardiac index (mean ± SD, l/min m²)	Non-responder	3.4 ± 1.2	3.5 ± 1.2	3.3 ± 1.2	3.4 ± 1.3^b
Stroke volume (mean ± SD, ml)	Responder	57.4 ± 22.7	69.5 ± 26.5^a	58.7 ± 22.3	71.7 ± 27.1^b
Stroke volume (mean ± SD, ml)	Non-responder	63.8 ± 27.6	64.4 ± 28.7	62.6 ± 27.6	65.3 ± 30.4^b
Stroke volume index (mean ± SD, ml/m²)	Responder	35.7 ± 14.0	43.4 ± 16.8^a	36.6 ± 13.9	44.8 ± 17.0^b
Stroke volume index (mean ± SD, ml/m²)	Non-responder	36.4 ± 15.6	36.7 ± 16.1	35.8 ± 15.7	37.3 ± 17.3^b
PtcO₂ (mean ± SD, mmHg)	Responder	90 ± 37	101 ± 38^a	92 ± 33	108 ± 39^b
PtcO₂ (mean ± SD, mmHg)	Non-responder	117 ± 37^c	116 ± 35	118 ± 37	116 ± 38
PtcCO₂ (mean ± SD, mmHg)	Responder	39 ± 7	39 ± 7^a	39 ± 7	39 ± 7
PtcCO₂ (mean ± SD, mmHg)	Non-responder	42 ± 13	41 ± 13	41 ± 13	41 ± 12

Responders refered to patients in whom volume expansion increased stroke volume ≥10% after 250 ml of rapid saline infusion in 10 min (n = 14). The remaining patients were defined as non-responders (n = 20)
PLR, passive leg raising; PtcO₂, transcutaneous partial pressure of oxygen; PtcCO₂, transcutaneous partial pressure of carbon dioxide
^a p < 0.05 versus before PLR; ^b p < 0.05 versus before volume expansion; ^c p < 0.05 versus responders

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