Table 3 Outcomes among patients with sepsis or septic shock in the three study phases: pre-intervention (A), intervention phase I (B) and intervention phase II (C) with adjustment to propensity scores
Variable | Pre-intervention A | Intervention phase I B | Intervention phase II C | Propensity scores adjusted OR or correlation coefficient* (95% CI, p value) | ||
|---|---|---|---|---|---|---|
All patients | N = 436 | N = 195 | N = 699 | B vs. A | C vs. B | C vs. A |
Hospital mortality, no. (%) | 208 (47.7) | 60 (30.8) | 118 (16.9) | 0.73 (0.48–1.09, 0.13) | 0.78 (0.51–1.17, 0.23) | 0.71 (0.58–0.85, 0.003) |
ICU LOS (days), mean ± SD | 13.3 ± 17.4 | 8.6 ± 8.3 | 5.1 ± 11.4 | −4.49 (−7.39 to −1.59, 0.002)* | −1.54 (−3.38 to 0.29, 0.09)* | −2.72 (−3.92 to −1.52, <0.0001)* |
Mechanical ventilation, no. (%) | 265 (60.8) | 54 (27.7) | 78 (11.2) | 0.33 (0.22–0.49, <0.0001) | 0.64 (0.41–0.99, 0.05) | 0.45 (0.37–0.55, <0.0001) |
ICU LOS among survivors (days), mean ± SD | 15.9 ± 19.5 | 11.9 ± 10.4 | 8.2 ± 13.8 | −5.88 (−11.44 to −0.22, 0.04)* | −1.05 (−5.22 to 3.10, 0.61)* | −3.55 (−6.13 to −0.98, 0.007)* |
Hospital LOS (days), mean ± SD | 29.3 ± 33.9 | 25.7 ± 40.9 | 15.3 ± 23.5 | −1.37 (−8.28 to 5.53, 0.70)* | −8.42 (−13.29 to −3.54, 0.0007)* | −5.35 (−7.76 to −2.94, <0.0001)* |
Hospital LOS among survivors (days), mean ± SD | 28.1 ± 30.8 | 24.7 ± 37.7 | 20.6 ± 28.6 | −1.76 (−12.09 to 8.57, 0.73)* | −6.22 (−16.9 to 4.48, 0.25)* | −3.45 (−7.83 to 0.92, 0.12)* |