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Table 2 Management of ARDS patients meeting ARDS criteria within 48 h of acute hypoxemic respiratory failure onset (n = 2813)

From: Etiologies, diagnostic work-up and outcomes of acute respiratory distress syndrome with no common risk factor: a prospective multicenter study

Parameters

ARDS patients with ≥1 risk factor identified (n = 2579)

ARDS patients with no risk factor identified (n = 234)

p valuea

Diagnostic procedures

   

Assessment of LHFP

1780 (68.4)

160 (69.4)

>0.99

 Echocardiography

1636 (63.4)

151 (64.5)

0.79

 Pulmonary artery catheter

103 (4.0)

14 (6.0)

0.20

 TTP

166 (6.4)

10 (4.3)

0.24

 Other methods

155 (6.0)

12 (5.1)

0.69

Chest CT scan

617 (23.9)

75 (32.1)

<0.01

  Number of chest CT scan

0 [0–0]

0 [0–1]

<0.01

Open lung biopsy

5 (0.2)

6 (2.6)

<0.01

Treatment of ARDS

   

Neuromuscular blocking agents

   

 In the 1st 72 h of ARDS

440 (17.1)

26 (11.1)

0.02

 At any time during ICU stay

517 (20.0)

33 (14.1)

0.04

Recruitment maneuvers

   

 In the 1st 72 h of ARDS

446 (17.3)

30 (12.8)

0.10

 At any time during ICU stay

506 (19.6)

33 (14.1)

0.05

Prone positioning

   

 In the 1st 72 h of ARDS

134 (5.2)

8 (3.4)

0.30

 At any time during ICU stay

190 (7.4)

11 (4.7)

0.17

ECMO

   

 In the 1st 72 h of ARDS

60 (2.3)

6 (2.6)

>0.99

 At any time during ICU stay

70 (2.7)

8 (3.4)

0.67

Inhaled vasodilators

   

 In the 1st 72 h of ARDS

156 (6.0)

7 (3.0)

0.08

 At any time during ICU stay

200 (7.9)

10 (3.8)

0.02

Corticosteroids

   

 In the 1st 72 h of ARDS

367 (14.2)

39 (16.7)

0.36

 At any time during ICU stay

467 (18.1)

41 (17.5)

0.89

  1. Categorical variables are shown as n (%)
  2. ARDS, acute respiratory distress syndrome; CT, computed tomography; LHFP, left heart filling pressure; TTP, transpulmonary thermodilution device; ICU, intensive care unit; ECMO, extracorporeal membrane oxygenation
  3. a p value represents comparisons across ARDS with or without known risk factor; parametric or nonparametric tests were used according to the distribution of variables