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Fig. 4 | Annals of Intensive Care

Fig. 4

From: A new global and comprehensive model for ICU ventilator performances evaluation

Fig. 4

Asynchrony index with or without the non-invasive ventilation mode. The asynchrony index (AI) is presented as mean ± SD and was measured under three different levels of exponential leaks (L1 = 3.5–4.0 L min−1; L2 = 5.0–7.0 L min−1; L3 = 9.0–12.5 L min−1) and three levels of inspiratory effort (P0.1 = 2, 4, 8 cmH2O). ‘Standard’ represents measurements performed under PC-CSV using unmodified manufacturers’ settings in terms of inspiratory and expiratory triggering; ‘NIV’ represents the measurements performed under the same conditions, while switching the ventilator to the NIV mode. Dotted line represents the 10% AI clinical level of significance. *p value <0.001. All ventilators presented an AI over 10% without NIV mode (‘standard’ invasive PC-CSV setting). Under the same leaks conditions, switching the ventilator to the NIV mode enabled a decrease in the AI to below a 10% value for the R860 and Servo-U. V500 and S1 measurements did not depict a significant impact of the NIV mode, while ‘standard’ settings provided rather satisfactory results in terms of leak management

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