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Fig. 1 | Annals of Intensive Care

Fig. 1

From: Assessment of renal hemodynamic toxicity of fluid challenge with 0.9% NaCl compared to balanced crystalloid (PlasmaLyte®) in a rat model with severe sepsis

Fig. 1

Experimental design. After catheter insertion and surgical CLP, rats were randomized into the 0.9% NaCl or PlasmaLyte® groups. After randomization (T0, supervision baseline), rats were hydrated with the corresponding crystalloid and were monitored until arterial pressure dropped below 90 mm Hg (T1, end of supervision, resuscitation baseline). At that time, they received the allocated crystalloid for 200 min for a targeted blood pressure of 90 mmHg. After 200 min, the animals were killed and their urine and plasma were sampled (T2, end of resuscitation)

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