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Table 3 Patient’s neurological and neurophysiological characteristics at time of inclusion

From: Early impairment of intracranial conduction time predicts mortality in deeply sedated critically ill patients: a prospective observational pilot study

Variables All patients Non-brain-injured patients Brain-injured patients p value
Number of patients 86 49 (57) 37 (43)  
Glasgow Coma Score—median (IQR) 3 (3 to 3) 3 (3 to 3) 3 (3 to 3) 0.97
FOUR score—median (IQR) 4 (2 to 5.7) 4 (2 to 5.0) 4 (2 to 5.5) 0.73
Abolition of cough reflex 24 (29) 16 (33) 8 (26) 0.34
RASS—median (IQR) −5 (−5 to −4) −5 (−5 to −4) −5 (−5 to −5) 0.82
Delayed SSEP’s IPL—n (%)
 N9–N13 IPL 14 (16) 11 (22) 3 (8) 0.08
 P14–N20 IPLa (ICCT) 39 (45) 21 (43) 18 (49) 0.60
Delayed BAEP’s IPL—n (%)     
 I–III IPL 17 (20) 9 (18) 8 (22) 0.71
 III–V IPL (IPCT) 15 (17) 9 (18) 6 (16) 0.80
 I–V IPL 17 (20) 12 (24) 5 (13) 0.21
  1. FOUR the Full Outline of Unresponsiveness (FOUR) score, RASS Richmond Assessment Sedation Scale, PL peak latency, IPL inter-peak latency, ICCT intracranial conduction time, IPCT intra pontine conduction time. PL and IPL of SSEP or BAEP’s components were scored as “delayed” when they were greater than the “mean + 2.5 SD” of the ones of a healthy control group
  2. aN20 was abolished in three patients. N20 PL and P14–N20 IPL were consequently considered as delayed for these three patients