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Table 2 Characteristics of in-hospital survivors and deceased

From: Red blood cell transfusion in the resuscitation of septic patients with hematological malignancies

Characteristics

In-hospital survivors (n = 370)

In-hospital deceased (n = 261)

p

Demographics

 Age (years)

58.5 [47–67.75]

63 [52–71]

0.01

 Male gender

240 (64.9%)

166 (63.6%)

0.81

Comorbid illnesses

 Performance status 3–4

61 (16.5%)

77 (29.5%)

0.0001

 Charlson comorbidity index

4 [2–5]

4 [3–6]

0.008

Underlying malignancy

  

0.90

 Lymphoid disease

179 (48.4%)

131 (50.2%)

 

 Myeloid disease

121 (32.7%)

83 (31.8%)

 

Time between diagnosis and ICU admission (days)

91 [14; 444]

90 [11; 396]

0.58

Hematopoietic stem cell transplantation

  

0.04

 Autologous

52 (14.1%)

24 (9.2%)

 

 Allogeneic

55 (14.9%)

55 (21.1%)

 

Malignancy status

  

0.019

 Newly diagnosed

106 (28.7%)

84 (32.2%)

 

 Partial/complete remission

116 (31.4%)

53 (21.4%)

 

Time between hospital and ICU admissions (days)

4 [0–16]

9 [1–25]

<0.0001

ICU admission characteristics

 SOFA score

6 [4–8]

8 [5–11.75]

<0.0001

 Neutropenia

125 (33.8%)

104 (39.9%)

0.14

 Lactate (mmol/L)

1.9 (1.125–3.575)

2.4 [1.6–5.6]

0.0001

Hemoglobin level (g/dL)

 Day 1

9.2 [8–10.7]

8.9 [7.8–10.2]

0.02

 Day 2

9.2 [8.3–10.2]

9.1 [8.3–10]

0.33

 Day 3

9 [8.1–10]

8.9 [8.2–9.975]

0.88

 Day 7

8.8 [8.1–9.8]

8.8 [8.3–9.95]

0.53

RBC transfusion

   

 Day 1 and/or 2

103 (27.8%)

107 (41%)

0.0008

 Day 3

42 (12.4%)

39 (17.3%)

0.13

 Day 7

16 (10.6%)

21 (16.7%)

0.19

Source of infection

 Pneumonia

190 (51.4%)

68 (64.3%)

0.002

 Abdominal

69 (18.7%)

34 (13.0%)

0.076

 Urinary tract

21 (5.7%)

15 (5.8%)

1.00

 Catheter-related

21 (5.7%)

7 (2.7%)

0.11

Pathogens

 Gram-negative bacteria

101 (27.3%)

74 (28.4%)

0.84

 Gram-positive bacteria

56 (15.1%)

25 (9.6%)

0.053

 Aspergillus

27 (7.3%)

42 (16.1%)

0.0008

 Pneumocystis

17 (4.6%)

5 (1.9%)

0.11

Life-supporting interventions

 Vasopressive drugs

184 (49.7%)

206 (78.9%)

<0.0001

 Invasive ventilation

124 (33.5%)

197 (75.5)

<0.0001

 Renal replacement therapy

56 (15.4%)

98 (38.7%)

<0.0001

  1. ICU intensive care unit, RBC red blood cell, SOFA sequential organ failure assessment