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Table 3 Main characteristics of the study population for ESBL acquisition and factors associated with ESBL acquisition in univariate analysis

From: Epidemiology of extended-spectrum beta-lactamase-producing Enterobacteriaceae in an intensive care unit with no single rooms

Variable All patients
n = 221
No ESBL acquisition
n = 212
ESBL acquisition
n = 9
p
Age (years) 67.0 [55.0, 77.0] 66.5 [55.0, 76.0] 82.0 [66.0, 82.0] 0.07
Age > 65 years 123 (55.6) 116 (54.7) 7 (78) 0.3
Male gender 144 (65.2) 137 (64.6) 7 (77.8) 0.5
SAPS II 49.0 [35.0, 66.0] 48.0 [35.0, 65.0] 72.0 [55.0, 77.0] 0.007
SOFA score 7.0 [4.0, 10.0] 7.0 [4.0, 10.0] 10.0 [9.0, 12.0] 0.01
Preexisting condition
 Heart failure 32 (14.5) 30 (14.1) 2 (28.6) 0.6
 Peripheral arterial disease 25 (11.3) 22 (10.3) 3 (33.3) 0.07
 Diabetes 54 (24.4) 51 (24) 3 (33.3) 0.5
 Cirrhosis 10 (4.5) 9 (4.2) 1 (11.1) 0.4
 Chronic obstructive pulmonary disease 39 (17.6) 37 (17.5) 2 (22.2) 0.7
 Chronic kidney disease 36 (16.3) 32 (15.1) 4 (44.4) 0.04
 Immunosuppression 38 (17.2) 36 (17.0) 2 (22.2) 0.7
Mechanical ventilation 166 (75.1) 157 (74.1) 9 (100) 0.1
Catecholamine use 132 (59.7) 123 (58.0) 9 (100) 0.01
Duration of mechanical ventilation (days) 4.0 [1.0, 10.0] 4.0 [0.0, 10.0] 9.0 [7.0, 11.0] 0.03
ICU length of stay (days) 8.0 [5.0, 12.0] 7.0 [5.0, 12.0] 11.0 [9.0, 26.0] 0.007
Transfer from another unit 124 (56.1) 117 (55.2) 7 (77.8) 0.3
Postoperative care 58 (26.2) 54 (25.5) 4 (44.4) 0.2
Hospitalization within the previous 3 months 123 (55.7) 117 (55.2) 6 (66.7) 0.7
Antibiotics within the previous 3 months 40 (18.1) 37 (17.5) 3 (33.3) 0.2
Antibiotics during ICU stay 193 (87.3) 184 (86.8) 9 (100) 0.6
Duration of antibiotic therapy 5.0 [3.0, 8.0] 5.0 [3.0, 8.0] 8.0 [5.0, 13.5] 0.1
  1. Categorical data are expressed as n (%)
  2. Quantitative data are expressed as median [IQR]