TY - STD TI - ECDC. European Centre for Disease Prevention and Control. Point prevalence survey of healthcareassociated infections and antimicrobial use in European acute care hospitals. Stockholm: ECDC; 2013. ID - ref1 ER - TY - STD TI - ECDC. Antimicrobial resistance surveillance in Europe 2014. Annual Report of the European Antimicrobial Resistance Surveillance Network (EARS-Net). Stockholm: European Centre for Disease Prevention and Control; 2015. ID - ref2 ER - TY - STD TI - European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2013. Annual Report of the European Antimicrobial Resistance Surveillance Network (EARS-Net). [Internet]. Ecdc; 2014. p. 1–211. ID - ref3 ER - TY - JOUR AU - Cobos-Trigueros, N. AU - Solé, M. AU - Castro, P. AU - Torres, J. L. AU - Hernández, C. AU - Rinaudo, M. PY - 2015 DA - 2015// TI - Acquisition of Pseudomonas aeruginosa and its resistance phenotypes in critically ill medical patients: role of colonization pressure and antibiotic exposure JO - Crit Care VL - 19 UR - https://doi.org/10.1186/s13054-015-0916-7 DO - 10.1186/s13054-015-0916-7 ID - Cobos-Trigueros2015 ER - TY - JOUR AU - Peña, C. AU - Suarez, C. AU - Tubau, F. AU - Dominguez, A. AU - Sora, M. AU - Pujol, M. PY - 2009 DA - 2009// TI - Carbapenem-resistant Pseudomonas aeruginosa: factors influencing multidrug-resistant acquisition in non-critically ill patients JO - Eur J Clin Microbiol Infect Dis VL - 28 UR - https://doi.org/10.1007/s10096-008-0645-9 DO - 10.1007/s10096-008-0645-9 ID - Peña2009 ER - TY - JOUR AU - Lodise, T. P. AU - Miller, C. AU - Patel, N. AU - Graves, J. AU - McNutt, L. A. PY - 2007 DA - 2007// TI - Identification of patients with Pseudomonas aeruginosa respiratory tract infections at greatest risk of infection with carbapenem-resistant isolates JO - Infect Control Hosp Epidemiol VL - 28 UR - https://doi.org/10.1086/518972 DO - 10.1086/518972 ID - Lodise2007 ER - TY - JOUR AU - Ong, D. S. AU - Jongerden, I. P. AU - Buiting, A. G. AU - Leverstein-van Hall, M. A. AU - Speelberg, B. AU - Kesecioglu, J. PY - 2011 DA - 2011// TI - Antibiotic exposure and resistance development in Pseudomonas aeruginosa and Enterobacter species in intensive care units JO - Crit Care Med. VL - 39 UR - https://doi.org/10.1097/CCM.0b013e318225756d DO - 10.1097/CCM.0b013e318225756d ID - Ong2011 ER - TY - JOUR AU - MacVane, S. H. AU - Kuti, J. L. AU - Nicolau, D. P. PY - 2014 DA - 2014// TI - Prolonging β-lactam infusion: a review of the rationale and evidence, and guidance for implementation JO - Int J Antimicrob Agents. VL - 43 UR - https://doi.org/10.1016/j.ijantimicag.2013.10.021 DO - 10.1016/j.ijantimicag.2013.10.021 ID - MacVane2014 ER - TY - JOUR AU - Vardakas, K. Z. AU - Tansarli, G. S. AU - Bliziotis, I. A. AU - Falagas, M. E. PY - 2013 DA - 2013// TI - β-Lactam plus aminoglycoside or fluoroquinolone combination versus β-lactam monotherapy for Pseudomonas aeruginosa infections: a meta-analysis JO - Int J Antimicrob Agents. VL - 41 UR - https://doi.org/10.1016/j.ijantimicag.2012.12.006 DO - 10.1016/j.ijantimicag.2012.12.006 ID - Vardakas2013 ER - TY - STD TI - Paul M, Dickstein Y, Schlesinger A, Grozinsky-Glasberg S, Soares-Weiser K, Leibovici L. Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia. Cochrane database Syst Rev [Internet]. 2013;6(6):CD003038. ID - ref10 ER - TY - JOUR AU - Moreno, R. P. AU - Metnitz, P. G. H. AU - Almeida, E. AU - Jordan, B. AU - Bauer, P. AU - Campos, R. A. PY - 2005 DA - 2005// TI - SAPS 3–from evaluation of the patient to evaluation of the intensive care unit. Part 2: development of a prognostic model for hospital mortality at ICU admission JO - Intensive Care Med VL - 31 UR - https://doi.org/10.1007/s00134-005-2763-5 DO - 10.1007/s00134-005-2763-5 ID - Moreno2005 ER - TY - STD TI - CLSI. Performance standards for antimicrobial susceptibility testing; twentieth informational supplement. CLSI document M100-S20. 2010; p. 1–153. ID - ref12 ER - TY - JOUR AU - Turnidge, J. AU - Paterson, D. L. PY - 2007 DA - 2007// TI - Setting and revising antibacterial susceptibility breakpoints JO - Clin Microbiol Rev. VL - 20 UR - https://doi.org/10.1128/CMR.00047-06 DO - 10.1128/CMR.00047-06 ID - Turnidge2007 ER - TY - JOUR AU - Chastre, J. AU - Wolff, M. AU - Fagon, J. Y. AU - Chevret, S. AU - Thomas, F. AU - Wermert, D. PY - 2003 DA - 2003// TI - Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial JO - J Am Med Assoc VL - 290 UR - https://doi.org/10.1001/jama.290.19.2588 DO - 10.1001/jama.290.19.2588 ID - Chastre2003 ER - TY - JOUR AU - Carmeli, Y. AU - Troillet, N. AU - Eliopoulos, G. M. AU - Samore, M. H. PY - 1999 DA - 1999// TI - Emergence of antibiotic-resistant Pseudomonas aeruginosa: comparison of risks associated with different antipseudomonal agents JO - Antimicrob Agents Chemother VL - 43 ID - Carmeli1999 ER - TY - JOUR AU - Georges, B. AU - Conil, J. -. M. AU - Dubouix, A. AU - Archambaud, M. AU - Bonnet, E. AU - Saivin, S. PY - 2006 DA - 2006// TI - Risk of emergence of Pseudomonas aeruginosa resistance to beta-lactam antibiotics in intensive care units JO - Crit Care Med VL - 34 UR - https://doi.org/10.1097/01.CCM.0000215517.51187.CA DO - 10.1097/01.CCM.0000215517.51187.CA ID - Georges2006 ER - TY - JOUR AU - Martínez, J. A. AU - Delgado, E. AU - Martí, S. AU - Marco, F. AU - Vila, J. AU - Mensa, J. PY - 2009 DA - 2009// TI - Influence of antipseudomonal agents on Pseudomonas aeruginosa colonization and acquisition of resistance in critically ill medical patients JO - Intensive Care Med VL - 35 UR - https://doi.org/10.1007/s00134-008-1326-y DO - 10.1007/s00134-008-1326-y ID - Martínez2009 ER - TY - JOUR AU - Feng, Y. AU - Jonker, M. J. AU - Moustakas, I. AU - Brul, S. AU - Kuile, B. H. PY - 2016 DA - 2016// TI - Dynamics of mutations during development of resistance by Pseudomonas aeruginosa against Five Antibiotics JO - Antimicrob Agents Chemother Internet VL - 60 UR - https://doi.org/10.1128/AAC.00434-16 DO - 10.1128/AAC.00434-16 ID - Feng2016 ER - TY - JOUR AU - Solé, M. AU - Fàbrega, A. AU - Cobos-Trigueros, N. AU - Zamorano, L. AU - Ferrer-Navarro, M. AU - Ballesté-Delpierre, C. PY - 2015 DA - 2015// TI - In vivo evolution of resistance of Pseudomonas aeruginosa strains isolated from patients admitted to an intensive care unit: mechanisms of resistance and antimicrobial exposure JO - J Antimicrob Chemother VL - 70 UR - https://doi.org/10.1093/jac/dkv228 DO - 10.1093/jac/dkv228 ID - Solé2015 ER - TY - JOUR AU - Tam, V. H. AU - Schilling, A. N. AU - Neshat, S. AU - Poole, K. AU - Melnick, D. A. AU - Coyle, E. A. PY - 2005 DA - 2005// TI - Optimization of meropenem minimum concentration/MIC ratio to suppress in vitro resistance of Pseudomonas aeruginosa JO - Antimicrob Agents Chemother VL - 49 UR - https://doi.org/10.1128/AAC.49.12.4920-4927.2005 DO - 10.1128/AAC.49.12.4920-4927.2005 ID - Tam2005 ER - TY - JOUR AU - Montmollin, E. AU - Bouadma, L. AU - Gault, N. AU - Mourvillier, B. AU - Mariotte, E. AU - Chemam, S. PY - 2014 DA - 2014// TI - Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen JO - Intensive Care Med VL - 40 UR - https://doi.org/10.1007/s00134-014-3276-x DO - 10.1007/s00134-014-3276-x ID - Montmollin2014 ER -