Fig. 2

Comparisons of a dosage; b aPPT values; in ARDS patients undergoing extracorporeal lung support with either argatroban or heparin as anticoagulant in the first consecutive 14 days of therapy left: argatroban; right: heparin. Data are presented as mean ± standard error of the mean (SEM) and were analyzed with a Mann–Whitney U test for nonparametric samples. *p < 0.05; **p < 0.01 compared to day 1. APTT activated thromboplastin time; µg/kg/min microgram per kilogram bodyweight per minute; IU/h international units per hour; s seconds; extracorporeal lung support: pECLA pumpless extracorporeal lung assist or ECMO extracorporeal membrane oxygenation