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Table 1 Patient characteristics

From: Assessment of sepsis-induced immunosuppression at ICU discharge and 6 months after ICU discharge

  Total study population n = 40 Patients with a blood sample at 6 months n = 15 Patients without a blood sample at 6 months n = 25 p value
Age (years), median (IQR) 68 (58–77) 62 (48–72) 71 (62–78) 0.08
Male gender, n (%) 21 (52.5) 8 (53.3) 13 (52.0) 1
SOFA score on day 1–2, median (IQR) 8 (7–9) 9 (7–10) 7 (6–9) 0.38
SAPS II, median (IQR) 53 (43–66) 52 (48–62) 53 (42–69) 0.71
Maximum lactate (mmol/L), median (IQR) 2.7 (1.8–3.7) 3.5 (2.5–5.9) 2.4 (1.7–2.9) 0.37
 Missing data, n 3   3  
Comorbidities, n (%)
 Chronic arterial hypertension 21 (52.5) 6 (40.0) 15 (60.0) 0.32
 Chronic heart failure 6 (15.0) 1 (6.7) 5 (20.0) 0.38
 Myocardial infarction 3 (7.5) 1 (6.7) 2 (8.0) 1
 Stroke 2 (5.0) 1 (6.7) 1 (4.0) 1
 Chronic obstructive pulmonary disease 9 (22.5) 2 (13.3) 7 (28.0) 0.44
 Dialysis-dependent chronic kidney disease 1 (2.5) 0 1 (4.0) 1
 Liver cirrhosis 0 0 0 1
 Diabetes mellitus 8 (20.0) 0 8 (32.0) 0.01
Source of infection, n (%)
 Abdominal 20 (50.0) 6 (40.0) 14 (56.0) 0.51
 Skin and soft tissue 7 (17.5) 1 (6.7) 6 (24.0) 0.22
 Respiratory 5 (12.5) 2 (13.3) 3 (12.0) 1
 Stomatological 3 (7.5) 3 (20.0) 0 0.04
 Urinary tract 3 (7.5) 2 (13.3) 1 (4.0) 0.54
 Osteoarticular 2 (5.0) 1 (6.7) 1 (4.0) 1
General management, n (%)
 Surgery 33 (82.5) 13 (86.7) 20 (80.0) 0.69
 Medical only 7 (17.5) 2 (13.3) 5 (20.0) 0.69
Support measures, n (%)
 Norepinephrine 40 (100.0) 15 (100.0) 25 (100.0) 1
 Dobutamine 5 (12.5) 1 (6.7) 4 (16.0) 0.63
 Mechanical ventilation 31 (77.5) 11 (73.3) 20 (80.0) 0.70
 Renal replacement therapy 12 (30.0) 4 (26.7) 8 (32.0) 1
Outcomes (days), median (IQR)
 Days on vasopressors 4 (3–5) 4 (3–10) 3 (2–5) 0.30
 Days on mechanical ventilation 6 (3–8) 7 (4–9) 5 (2–7) 0.43
  Patients involved, n 31 11 20  
 Days on renal replacement therapy 8 (6–8) 10 (8–12) 7 (4–8) 0.05
  Patients involved, n 12 4 8  
 ICU length of stay 11 (7–24) 13 (6–25) 10 (7–24) 0.86
 Hospital length of stay 37 (16–48) 37 (19–46) 37 (19–49) 0.75
  1. IQR interquartile range, SOFA Sepsis-related Organ Failure Assessment, SAPS II Simplified Acute Physiology Score II, ICU intensive care unit