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Table 2 Biological parameters

From: Assessment of sepsis-induced immunosuppression at ICU discharge and 6 months after ICU discharge

  Total study population n = 40 Patients with a blood sample at 6 months n = 15 Patients without a blood sample at 6 months n = 25 p value
Leukocytes (mm−3 × 103), median (IQR)
 D1-2 16.6 (10.4–22.1) 15.3 (7.3–22.1) 16.6 (13.0–20.7) 0.41
  Missing data, n 1 0 1  
 D3-4 15.8 (10.1–21.3) 14.6 (10.6–21.5) 15.8 (9.7–19.7) 0.75
  Missing data, n 9 1 8  
 D6-8 14.2 (12.7–19.3) 13.8 (10.8–15.8) 15.4 (12.8–19.5) 0.88
  Missing data, n 15 5 10  
Neutrophils (mm−3 × 103), median (IQR)
 D1-2 13.7 (7.8–20.0) 13 (6.3–20.0) 13.9 (10.4–19.1) 0.47
  Missing data, n 1 0 1  
 D3-4 13 (8.8–18.5) 12.7 (9.5–18.9) 12.8 (8.4–16.3) 0.67
  Missing data, n 9 1 8  
 D6-8 11.8 (9.0–16.2) 11.6 (8.5–13.7) 12 (9.7–16.5) 0.76
  Missing data, n 15 5 10  
Lymphocytes (mm−3 × 103), median (IQR)
 D1-2 1 (0.5–1.5) 0.5 (0.3–0.9) 1.1 (0.7–1.8) 0.83
  Missing data, n 1 0 1  
 D3-4 1 (0.7–1.4) 1 (0.9–1.2) 1 (0.6–2.0) 0.99
  Missing data, n 9 1 8  
 D6-8 1.3 (1.0–2.2) 1.1 (1.0–1.3) 2 (1.0–2.2) 0.17
  Missing data, n 15 5 10  
Monocytes (mm−3 × 103), median (IQR)
 D1-2 0.5 (0.3–0.9) 0.4 (0.3–0.6) 0.6 (0.37–1.12) 0.78
  Missing data, n 1 0 1  
 D3-4 0.6 (0.4–0.9) 0.6 (0.4–0.7) 0.55 (0.42–1.0) 0.84
  Missing data, n 9 1 8  
 D6-8 0.7 (0.4–0.8) 0.4 (0.6–0.7) 0.7 (0.61–1.1) 0.35
  Missing data, n 15 5 10  
mHLA-DR (AB/C), median (IQR)
 D1-2 4212 (2640–6047) 3321 (2246–6022) 4486 (2673–6047) 0.41
  Missing data, n 4 3 1  
 D3-4 4514 (3232–6497) 4989 (1484–7379) 4235 (3365–5555) 0.51
  Missing data, n 1 1 0  
 D6-8 7442 (4315–9724) 4817 (3059–9143) 7808 (5070–10,249) 0.13
  Missing data, n 8 4 4  
 ICU discharge 10,281 (7719–13,035) 10,228 (8719–11,826) 11,271 (7195–16,594) 0.54
  Missing data, n 7 2 5  
 6 months post-ICU discharge 32,616 (24,918–38,738) 32,616 (24,918–38,738)   
 Missing data, n 25 0   
CD4+ T cells (mm−3), median (IQR)
 D3-4 515 (343–724) 477 (356–670) 537 (344–963) 0.63
  Missing data, n 1 1 0  
 ICU discharge 642 (459–846) 765 (459–796) 628 (463–979) 0.85
  Missing data, n 11 6 5  
 6 months post-ICU discharge 797 (647–1057) 797 (647–1057)   
  Missing data, n 26 1   
Treg percentage, median (IQR)
 D3-4 6.6 (5.0–9.3) 7 (5.1–10.8) 6.4 (4.9–9.0) 0.54
  Missing data, n 1 1 0  
 ICU discharge 6.6 (5.2–7.9) 6.6 (5.0–8.3) 6.53 (5.5–7.6) 0.80
  Missing data, n 11 6 5  
 6 months post-ICU discharge 6.4 (4.7–8.0) 6.4 (4.7–8.0)   
  Missing data, n 26 1   
Absolute Treg (mm−3), median (IQR)
 D3-4 35 (22–45) 34 (22–43) 35 (23–47) 0.92
  Missing data, n 1 1 0  
 ICU discharge 39 (28–64) 39 (28–64) 38 (28–77) 0.85
  Missing data, n 11 6 5  
 6 months post-ICU discharge 44 (34–67) 44 (34–67)   
  Missing data, n 26 1   
  1. IQR interquartile range, AB/C anti-HLA-DR antibodies per cell, ICU intensive care unit