From: Association between elevated central venous pressure and outcomes in critically ill patients
Quartiles of mean CVP level | ||||
---|---|---|---|---|
1 (n = 2281) | 2 (n = 2269) | 3 (n = 2277) | 4 (n = 2263) | |
Mean CVP/mmHg | 7.4 (1.9) | 10.6 (1.9) | 13.1 (2.2) | 17.4 (4.1) |
Median CVP/mmHg | 7 | 10 | 13 | 16 |
Age (years) | 67.1 (15.8) | 66.9 (15.9) | 65.8 (15.5) | 64.4 (15.4) |
Sex, male | 1070 (57.9%) | 1088 (58.9%) | 1046 (56.7%) | 1007 (54.6%) |
Ethnicity, n (%) | ||||
Asian | 33 (1.8%) | 40 (2.2%) | 21 (1.1%) | 37 (2.0%) |
Black | 101 (5.5%) | 114 (6.2%) | 99 (5.4%) | 119 (6.4%) |
White | 1326 (71.8%) | 1301 (70.5%) | 1297 (70.3%) | 1293 (70.1%) |
Latino | 47 (2.5%) | 41 (2.2%) | 58 (3.1%) | 57 (3.1%) |
Other | 341 (18.5%) | 350 (19.0%) | 370 (20.1%) | 339 (18.4%) |
ICU type | ||||
Medical | 437 (23.6%) | 440 (23.8%) | 481 (26.1%) | 601 (32.6%) |
Surgical | 335 (18.1%) | 238 (12.9%) | 272 (14.7%) | 293 (15.9%) |
Trauma surgical | 227 (12.3%) | 198 (10.7%) | 203 (11.0%) | 167 (9.1%) |
Cardiac surgery recovery | 647 (35.0%) | 739 (40.0%) | 654 (35.4%) | 558 (30.2%) |
Coronary | 202 (10.9%) | 231 (12.5%) | 235 (12.7%) | 226 (12.2%) |
Comorbidities | ||||
Congestive heart failure | 265 (14.3%) | 277 (15.0%) | 359 (19.5%) | 363 (19.7%) |
Cardiac arrhythmias | 288 (15.6%) | 291 (15.8%) | 328 (17.8%) | 408 (22.1%) |
Hypertension | 134 (7.3%) | 170 (9.2%) | 162 (8.8%) | 659 (34.2%) |
Valvular disease | 88 (4.8%) | 78 (4.2%) | 117 (6.3%) | 119 (6.4%) |
Pulmonary circulation disease | 63 (3.4%) | 54 (2.9%) | 78 (4.2%) | 100 (5.4%) |
Renal failure | 167 (9.0%) | 199 (10.8%) | 202 (10.9%) | 310 (16.8%) |
Admission status | ||||
Admission SAPS, points | 20.6 (4.7) | 21.2 (4.8) | 21.9 (4.9) | 23.0 (4.9) |
Mean duration of CVP measurement (h) | 40.55 (19.78) | 22.88 (10.27) | 51.25 (16.97) | 60.24 (12.56) |
Mean duration of ECVP10 (h) | 5.65 (6.10) | 20.60 (11.54) | 35.70 (16.06) | 47.90 (17.55) |
ICU outcome | ||||
28-day mortality (%) | 15.4 | 16.8 | 17.3 | 22.8 |
Length of hospitalization (day) | 15.4 (14.1) | 15.4 (13.4) | 16.1 (13.3) | 17.8 (15.8) |
Length of ICU stay (day) | 6.9 (7.1) | 7.8 (8.0) | 9.3 (9.7) | 11.0 (10.9) |
Selected laboratory test | ||||
WBC max, k/μL | 19.1 (9.7) | 19.9 (11.1) | 20.4 (16.2) | 21.4 (12.7) |
Lactate max (mmol/L) | 2.9 (2.6) | 3.2 (3.1) | 3.6 (3.2) | 4.9 (4.5) |
Creatinine max (mg/dL) | 1.9 (1.9) | 2.1 (2.0) | 2.3 (3.5) | 2.8 (2.7) |
Total bilirubin max (μmol/L) | 1.7 (4.8) | 1.8 (4.3) | 2.4 (5.9) | 4.0 (8.2) |
Treatment received | ||||
Duration of vasopressor (day) | 1.8 (4.4) | 2.6 (5.4) | 3.6 (7.1) | 4.9 (8.4) |
Duration of ventilator (day) | 3.8 (6.9) | 4.8 (8.0) | 6.5 (9.7) | 7.9 (11.0) |
Fluid balance [L, Median (IQR)] | 3.9 (0.7, 8.0) | 4.6 (1.3, 9.0) | 5.3 (2.0, 10.1) | 6.8 (3.0, 12.8) |