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Table 1 General patient characteristics stratified by quartiles of mean CVP level during the first 72 h from ICU admission

From: Association between elevated central venous pressure and outcomes in critically ill patients

 

Quartiles of mean CVP level

1 (n = 2281)

2 (n = 2269)

3 (n = 2277)

4 (n = 2263)

Mean CVP/mmHg

7.4 (1.9)

10.6 (1.9)

13.1 (2.2)

17.4 (4.1)

Median CVP/mmHg

7

10

13

16

Age (years)

67.1 (15.8)

66.9 (15.9)

65.8 (15.5)

64.4 (15.4)

Sex, male

1070 (57.9%)

1088 (58.9%)

1046 (56.7%)

1007 (54.6%)

Ethnicity, n (%)

 Asian

33 (1.8%)

40 (2.2%)

21 (1.1%)

37 (2.0%)

 Black

101 (5.5%)

114 (6.2%)

99 (5.4%)

119 (6.4%)

 White

1326 (71.8%)

1301 (70.5%)

1297 (70.3%)

1293 (70.1%)

 Latino

47 (2.5%)

41 (2.2%)

58 (3.1%)

57 (3.1%)

 Other

341 (18.5%)

350 (19.0%)

370 (20.1%)

339 (18.4%)

ICU type

 Medical

437 (23.6%)

440 (23.8%)

481 (26.1%)

601 (32.6%)

 Surgical

335 (18.1%)

238 (12.9%)

272 (14.7%)

293 (15.9%)

 Trauma surgical

227 (12.3%)

198 (10.7%)

203 (11.0%)

167 (9.1%)

 Cardiac surgery recovery

647 (35.0%)

739 (40.0%)

654 (35.4%)

558 (30.2%)

 Coronary

202 (10.9%)

231 (12.5%)

235 (12.7%)

226 (12.2%)

Comorbidities

 Congestive heart failure

265 (14.3%)

277 (15.0%)

359 (19.5%)

363 (19.7%)

 Cardiac arrhythmias

288 (15.6%)

291 (15.8%)

328 (17.8%)

408 (22.1%)

 Hypertension

134 (7.3%)

170 (9.2%)

162 (8.8%)

659 (34.2%)

 Valvular disease

88 (4.8%)

78 (4.2%)

117 (6.3%)

119 (6.4%)

 Pulmonary circulation disease

63 (3.4%)

54 (2.9%)

78 (4.2%)

100 (5.4%)

 Renal failure

167 (9.0%)

199 (10.8%)

202 (10.9%)

310 (16.8%)

Admission status

 Admission SAPS, points

20.6 (4.7)

21.2 (4.8)

21.9 (4.9)

23.0 (4.9)

 Mean duration of CVP measurement (h)

40.55 (19.78)

22.88 (10.27)

51.25 (16.97)

60.24 (12.56)

 Mean duration of ECVP10 (h)

5.65 (6.10)

20.60 (11.54)

35.70 (16.06)

47.90 (17.55)

ICU outcome

 28-day mortality (%)

15.4

16.8

17.3

22.8

 Length of hospitalization (day)

15.4 (14.1)

15.4 (13.4)

16.1 (13.3)

17.8 (15.8)

 Length of ICU stay (day)

6.9 (7.1)

7.8 (8.0)

9.3 (9.7)

11.0 (10.9)

Selected laboratory test

 WBC max, k/μL

19.1 (9.7)

19.9 (11.1)

20.4 (16.2)

21.4 (12.7)

 Lactate max (mmol/L)

2.9 (2.6)

3.2 (3.1)

3.6 (3.2)

4.9 (4.5)

 Creatinine max (mg/dL)

1.9 (1.9)

2.1 (2.0)

2.3 (3.5)

2.8 (2.7)

 Total bilirubin max (μmol/L)

1.7 (4.8)

1.8 (4.3)

2.4 (5.9)

4.0 (8.2)

Treatment received

 Duration of vasopressor (day)

1.8 (4.4)

2.6 (5.4)

3.6 (7.1)

4.9 (8.4)

 Duration of ventilator (day)

3.8 (6.9)

4.8 (8.0)

6.5 (9.7)

7.9 (11.0)

 Fluid balance [L, Median (IQR)]

3.9 (0.7, 8.0)

4.6 (1.3, 9.0)

5.3 (2.0, 10.1)

6.8 (3.0, 12.8)

  1. Values are presented as mean (SD), unless otherwise stated
  2. CVP central venous pressure, IQR interquartile range, ICU intensive care unit, WBC white blood cell, SAPS Simplified Acute Physiology Score