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Table 1 Patient demographics

From: Opioid-associated iatrogenic withdrawal in critically ill adult patients: a multicenter prospective observational study

Characteristics IWS-negative (n = 45) IWS-positive (n = 9) All patients (n = 54)
Median age (year) (25th–75th percentile) 53 (40.5–66) 46 (26–59) 50 (38.2–64.5)
Male, no (%) 34 (75.6) 6 (66.3) 40 (74.1)
Median APACHE II (25th–75th percentile) 22 (15.5–28.5) 25 (13–31) 22 (12–28.2)
Median weight (kg) (25th–75th percentile) 85 (79–100) 75 (67.2–95.7) 83.5 (75.8–98.4)
Creatinine ICU adm (μmol/L) (25th–75th percentile) 122 (87–179.5) 106 (72–315) 116 (87–209)
Length of mechanical ventilation (h) 188 (120–358) 286 (197–789.5) 226.5 (124.3–380.3)
Median length of ICU stay, days (IQR) 17 (9.5–22.5) 21 (11–42.5) 17.5 (10–23)
Reason of admission (ICD-10) n (%)    
 External causes of morbidity (e.g., trauma) 17 (37.8) 4 (44.4) 21 (38.9)
 Diseases of the respiratory system 8 (17.8) 0 8 (14.8)
 Symptoms and signs not elsewhere classified 4 (8.9) 3 (33.3) 7 (13.0)
 Circulatory system 7 (15.6) 0 7 (13.0)
 Digestive system 3 (6.7) 0 3 (5.6)
 Musculoskeletal/connective tissues 2 (4.4) 1 (11.1) 3 (5.6)
 Nervous system 1 (2.2) 1 (11.1) 2 (3.7)
 Other categories 3 (6.6) 0 (0) 3 (5.6)