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Annals of Intensive Care
Fig. 2 | Annals of Intensive Care

Fig. 2

From: Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats

Fig. 2

Effect of fluid resuscitation on kidney function in CS rats. a Hematoxylin and eosin-stained kidney sections following reperfusion for 3 h, b hematoxylin and eosin-stained kidney sections following reperfusion for 24 h, c urine NAG concentration, d plasma NAG concentration, e urine KIM-1/Cre ratio, and f kidney HO-1/β-actin ratio. White bar sham, black bar CS-only, gray bar C-saline, and shaded bar C-AS. Values represent mean ± SEM (n = 3). # p < 0.05 versus sham group, *p < 0.05 versus CS-only group; and † p < 0.05 versus C-saline group (Tukey’s test). Micrographs are representative of three independent experiments (×200 magnification; scale bars 100 μm). Black arrowhead dilated kidney tubule. CS crush syndrome, NAG N-acetyl-β-d-glucosaminidase, KIM-1 kidney injury marker-1, Cre creatinine, HO-1 heme oxygenase-1

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