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Annals of Intensive Care
Fig. 4 | Annals of Intensive Care

Fig. 4

From: Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats

Fig. 4

Effect of fluid resuscitation on NO mechanism in CS rats. a Muscle NO2 −, b muscle NO3 −, c muscle p-eNOS/eNOS ratio, and d muscle iNOS/β-actin ratio. White bar sham, black bar CS-only, gray bar C-saline, and shaded bar C-AS. Values represent mean ± SEM (n = 3). # p < 0.05 versus sham group, *p < 0.05 versus CS-only group, and † p < 0.05 versus C-saline group (Tukey’s test). CS crush syndrome, NO nitric oxide, eNOS endothelial nitric oxide synthase, iNOS inducible nitric oxide synthase

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