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Fig. 5 | Annals of Intensive Care

Fig. 5

From: Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats

Fig. 5

Effect of fluid resuscitation on mitochondrial function, antioxidant action, and low-oxygen injury in CS rats. a Cytoplasm cyt c content, b muscle JC-1 fluorescence, c muscle TBARS ratio, d muscle SOD activity, e muscle HO-1/β-actin ratio, and f muscle HIF-1α/β-actin ratio. White bar sham, black bar CS-only, gray bar C-saline and, shaded bar C-AS. Values represent mean ± SEM (n = 3). # p < 0.05 versus sham group, *p < 0.05 versus CS-only group, and p < 0.05 versus C-saline group (Tukey’s test). CS crush syndrome, cyt c cytochrome c, TBARS thiobarbituric acid reactive substances, SOD superoxide dismutase, HO-1 heme oxygenase-1, HIF-1α hypoxia-inducible factor-1 alpha

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