Table 3 Univariate analysis of patient characteristics according to the occurrence of thromboembolic events
Variables | TEE+ (n = 47) | TEE− (n = 106) | p |
|---|---|---|---|
Demographic characteristics | |||
Age (years) | 46.8 ± 18.4 | 43.6 ± 19.8 | 0.3505 |
Sex (male) | 80.9% (38) | 67.9% (72) | 0.6140 |
BMI (kg/m2) | 26.6 ± 7.1 | 25.9 ± 6.2 | 0.5571 |
History of cancer | 0% (0) | 6 (5.7%) | 0.2253 |
History of DVT | 0% (0) | 0% (0) | – |
Injuries grading | |||
Initial GCS ≤ 8 | 29.8% (14) | 17.9% (19) | 0.1519 |
AIS thorax > 2 | 46.8% (22) | 36.8% (39) | 0.3230 |
AIS head > 2 | 40.4% (19) | 43.4% (46) | 0.8684 |
AIS abdomen > 2 | 27.6% (13) | 17.9% (19) | 0.2500 |
Pelvic fracture | 29.8% (14) | 12.3% (13) | 0.0167 |
Lower limbs fracture | 25.5% (12) | 28.3% (30) | 0.8746 |
Medullar injury | 25.53% (12) | 9.43% (10) | 0.0179 |
Spine fracture | 42.6% (20) | 24.5% (26) | 0.0402 |
Scores | |||
SAPS II | 44.9 [38.7; 50.7] | 30.4 [27.4; 34.1] | 0.0001 |
ISS | 28.9 [20; 34] | 21.4 [13; 29] | 0.0006 |
SOFA 24 h | 8.3 [5; 11] | 5.6 [1; 9.5] | 0.0007 |
RAP score > 5 | 95.7% (45) | 83% (88) | 0.0582 |
RAP score > 10 | 70.2% (33) | 39.6% (42) | 0.0009 |
Clinical status | |||
SAP min (mmHg) | 99 ± 28 | 111 ± 25 | 0.0083 |
Vasopressors | 31.9% (15) | 18.1% (19) | 0.0594 |
Surgery > 2 h | 46.8% (22) | 30.2% (32) | 0.0782 |
Central venous catheter | 95.7% (45) | 74.5% (79) | 0.0041 |
Initial transfusion treatment (day 1) | |||
Transfusion > 4 RBC in 6 h | 29.8% (14) | 13.2% (14) | 0.0264 |
Tranexamic acid | 36.2% (17) | 17.9% (19) | 0.0246 |
Fibrinogen | 31.9% (15) | 13.2% (14) | 0.0124 |
Thromboprophylactic procedure | |||
Compression stockings (absent) | 8.5% (4) | 9.5% (10) | 0.9769 |
Pneumatic intermittent compression (no) | 14.9% (7) | 18.1% (19) | 0.8877 |
Time before initiation of antithrombotic chemoprophylaxis | 2 [1; 2] | 1 [1; 2] | 0.4533 |
Outcome | |||
ICU length of stay | 18 [7; 32] | 5.5 [3; 11] | <0.0001 |
Hospital length of stay | 28 [15; 43] | 17 [11; 28] | 0.0027 |
Mortality | 10.6% (5) | 10.4% (11) | 0.5976 |
Binarized characteristics | |||
ISS ≥ 16 | 87.2% (41) | 69.6% (73) | 0.0333 |
SAPS II ≥ 30 | 76.6% (36) | 47.6% (49) | 0.0016 |
SOFA 24 ≥ 5 | 80.9% (38) | 50.9% (54) | 0.0009 |
BMI ≥ 30 kg/m2 | 23.9% (11) | 24.7% (21) | 1 |
Age ≥ 50 years | 40.4% (19) | 34.6% (36) | 0.614 |
SAP min ≤ 80 mmHg | 26.1 (12) | 7.8% (8) | 0.0061 |
GCS ≤ 8 | 25.5% (12) | 18.9% (20) | 0.4718 |