Fig. 5

a Hierarchical summary receiver operating characteristic plot of presepsin across all included studies. b Comparisons of presepsin and C-reactive protein with summary receiver operating characteristic curves. c Comparisons of presepsin and procalcitonin with summary receiver operating characteristic curves. Note the red circle represents the summary estimate for presepsin, the blue triangle represents the summary estimate for procalcitonin, and the blue diamond represents the summary estimate for C-reactive protein. The ellipse represents the confidence region for each summary estimate