Table 5 Summaries of pooled sensitivity and specificity of presepsin to diagnose sepsis for different compositions of control group
Case | Control | Number of studies | Number of patients | Pooled sensitivity | Pooled specificity | AUC | Pooled DOR | Median cut-off |
|---|---|---|---|---|---|---|---|---|
Sepsis | Healthy | 5 | 546 | 0.88 (0.70–0.96) | 0.82 (0.75–0.88) | 0.88 | 26 (9–75) | 618 |
Sepsis | Mixed | 5 | 1397 | 0.86 (0.76–0.92) | 0.68 (0.47–0.83) | 0.86 | 15 (9–23) | 574 |
Sepsis | Non-infectious SIRS | 8 | 1527 | 0.81 (0.76–0.85) | 0.71 (0.63–0.78) | 0.84 | 10 (8–15) | 533 |