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Table 5 Summaries of pooled sensitivity and specificity of presepsin to diagnose sepsis for different compositions of control group

From: Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C-reactive protein: a systematic review and meta-analysis

Case Control Number of studies Number of patients Pooled sensitivity Pooled specificity AUC Pooled DOR Median cut-off
Sepsis Healthy 5 546 0.88 (0.70–0.96) 0.82 (0.75–0.88) 0.88 26 (9–75) 618
Sepsis Mixed 5 1397 0.86 (0.76–0.92) 0.68 (0.47–0.83) 0.86 15 (9–23) 574
Sepsis Non-infectious SIRS 8 1527 0.81 (0.76–0.85) 0.71 (0.63–0.78) 0.84 10 (8–15) 533