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Annals of Intensive Care
Fig. 2 | Annals of Intensive Care

Fig. 2

From: Cell-cycle arrest biomarkers in urine to predict acute kidney injury in septic and non-septic critically ill patients

Fig. 2

Boxplot comparing the worst [TIMP-2]·[IGFBP7] index and sCr upon admittance with the worst AKIN. Boxplots indicate the median, 25th and 75th percentiles. Whiskers indicate the 5th and 95th percentiles. Statistical significance (p) comparing each biomarker index with AKIN and RIFLE categories. p was determined by Kruskal–Wallis test, not correlation. We found statistical differences in the worst [TIMP-2]·[IGFBP7] index concentrations when comparing the subgroup without AKI with any degree of AKI defined by AKIN. Between non-AKI and AKIN 1, p was 0.014 and p < 0.001 when comparing with AKIN 2 and AKIN 3. In between AKIN 1 and AKIN 3, p = 0.004, whereas in between AKIN 2 and AKIN 3 p = 0.039. When comparing sCr levels with AKIN, we found differences between the subgroup without AKI with AKIN 1 (p = 0.008), AKIN 2 and 3 (for both p < 0.001). In between AKIN 1 and 3, p was 0.048 and p = 0.033 in AKIN 2 versus AKIN 3

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