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Table 3 Patient characteristics, severity scores at admission, ventilator and respiratory mechanics parameters at admission and clinical outcome data in the three groups of patients included in the study

From: Interstitial pneumonia with autoimmune features: an additional risk factor for ARDS?

  ARDS with known risk factors No risk factors IPAF p
Gender (male) 54 (69%) 1 (25%) 4 (57%) 0.763
Age (years) 55 (45–67.25) 58.5 (38.5–72.25) 61 (50–66) 0.726
SAPS II 41.5 (31–50.5) 42 (35–59) 32 (32–37) 0.133
SOFA 8 (5.75–12) 8.5 (8–11) 11 (11–13) 0.068
PaO2/FiO2 (mmHg) 93 (67.75–125.25) 103 (62.75–150.75) 120 (80–141) 0.515
PEEP (mmHg) 12.5 (10–15) 10 (7.25–14.75) 12 (10–14) 0.303
Compliance (mL/cmH2O) 29.4 (24–37) 26.5 (16.25–43.5) 26 (14–30) 0.336
Intrapulmonary shunt (%) 35 (25–46.5) 33 (14.5–40.5) 35 (25.5–52.5) 0.588
Plateau pressure (cmH2O) 28 (26–30) 27.5 (22.5–29.75) 26 (25–30) 0.796
Driving pressure (cmH2O) 14 (11–18) 15.5 (10.25–21.25) 14 (12–18) 0.977
ECMO 32 (41%) 2 (25%) 5 (71%) 0.176
Tracheostomy 45 (58%) 3 (43%) 5 (71%) 0.557
Pronation 41 (53%) 3 (43%) 6 (86%) 0.197
Survival 55 (71%) 3 (38%) 5 (71%) 0.159
ICU length of stay (days) 19 (8.75–32.25)* 15.5 (5.5–35.75)* 54 (23–84) 0.045
ECMO duration (days) 9.5 (6–13)* 28 (8–48) 53 (17–63) 0.006
IMV duration (days) 17 (6–28.5)* 15.5 (5.5–34.25)* 49 (21–81) 0.031
  1. Data are presented as absolute frequency (% of the included patients) or as median and interquartile range
  2. IPAF interstitial pneumonia with autoimmune features, SAPS II Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment, PEEP positive end-expiratory pressure, ECMO extracorporeal membrane oxygenation, ICU intensive care unit, IMV invasive mechanical ventilation
  3. p < 0.05 versus IPAF group