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Table 3 Predictors of 1-year mortality: univariate and multivariate analysis

From: Protective effect of early low-dose hydrocortisone on ventilator-associated pneumonia in the cancer patients: a propensity score analysis

Variables Univariate Multivariate
HR 95% CI P HR 95% CI P
Male gender 0.89 0.64–1.24 0.49    
Age 0.99 0.98–1 0.13    
Cancer type       
 Haematological malignancy 1 (Reference) 0.91    
 Solid tumour 0.91 0.65–1.28     
Cancer stage       
 Complete remission 1 (Reference) 0.02 1 (Reference) 0.03
 Diagnosis 1.37 0.87–2.16   1.44 0.88–2.35  
 Partial remission 0.82 0.50–1.33   0.98 0.57–1.68  
 Evolutive 1.54 0.99–2.41   1.77 1.10–2.87  
HSCT 1.28 0.86–1.92 0.23    
Admission purpose       
 Others 1 (Reference) 0.055    
 Septic shock 0.96 0.54–1.71     
 Acute respiratory failure 0.62 0.34–1.11     
 Coma 0.66 0.31–1.43     
Clinical sepsis upon admission       
 None 1 (Reference) 0.02 1 (Reference) 0.04
 Respiratory 1.67 1.09–2.56   1.65 1.03–2.65  
 Non-respiratory 1.91 1.16–3.15   1.78 1.01–3.15  
Characteristics upon admission       
 Neutropenia 1.41 1.02–1.94 0.04    
 Antibiotherapy 1.18 0.80–1.72 0.4    
 Corticosteroids (curative) 1.03 0.73–1.45 0.89    
SOFA score (day of intubation) 1.10 1.06–1.15 0.0001 1.11 1.05–1.17 0.0002
Characteristics at the first 48 h of MV       
 Vasopressors 1.34 0.93–1.94 0.11    
 Renal replacement therapy 1.45 1.00–2.12 0.06    
 Substitutive hydrocortisone 1.28 0.92–1.77 0.28    
 G-CSF 1.85 1.23–2.78 0.005 1.65 1.03–2.65 0.042
 Enteral nutrition 1.17 0.68–2.00 0.58    
 Antibiotherapy       
  Adapted, n (%) 1 (Reference) 0.83    
  Empirical, n (%) 0.85 0.6–1.22     
  None, n (%) 0.96 0.5–1.86     
VAP 1.41 0.98–2.03 0.06 1.60 1.10–2.34 0.017
  1. HSCT haematopoietic stem cell transplantation, G-CSF granulocyte colony-stimulating factors, MV mechanical ventilation, VAP ventilator-associated pneumonia