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Table 3 Predictors of 1-year mortality: univariate and multivariate analysis

From: Protective effect of early low-dose hydrocortisone on ventilator-associated pneumonia in the cancer patients: a propensity score analysis

Variables

Univariate

Multivariate

HR

95% CI

P

HR

95% CI

P

Male gender

0.89

0.64–1.24

0.49

   

Age

0.99

0.98–1

0.13

   

Cancer type

      

 Haematological malignancy

1

(Reference)

0.91

   

 Solid tumour

0.91

0.65–1.28

    

Cancer stage

      

 Complete remission

1

(Reference)

0.02

1

(Reference)

0.03

 Diagnosis

1.37

0.87–2.16

 

1.44

0.88–2.35

 

 Partial remission

0.82

0.50–1.33

 

0.98

0.57–1.68

 

 Evolutive

1.54

0.99–2.41

 

1.77

1.10–2.87

 

HSCT

1.28

0.86–1.92

0.23

   

Admission purpose

      

 Others

1

(Reference)

0.055

   

 Septic shock

0.96

0.54–1.71

    

 Acute respiratory failure

0.62

0.34–1.11

    

 Coma

0.66

0.31–1.43

    

Clinical sepsis upon admission

      

 None

1

(Reference)

0.02

1

(Reference)

0.04

 Respiratory

1.67

1.09–2.56

 

1.65

1.03–2.65

 

 Non-respiratory

1.91

1.16–3.15

 

1.78

1.01–3.15

 

Characteristics upon admission

      

 Neutropenia

1.41

1.02–1.94

0.04

   

 Antibiotherapy

1.18

0.80–1.72

0.4

   

 Corticosteroids (curative)

1.03

0.73–1.45

0.89

   

SOFA score (day of intubation)

1.10

1.06–1.15

0.0001

1.11

1.05–1.17

0.0002

Characteristics at the first 48 h of MV

      

 Vasopressors

1.34

0.93–1.94

0.11

   

 Renal replacement therapy

1.45

1.00–2.12

0.06

   

 Substitutive hydrocortisone

1.28

0.92–1.77

0.28

   

 G-CSF

1.85

1.23–2.78

0.005

1.65

1.03–2.65

0.042

 Enteral nutrition

1.17

0.68–2.00

0.58

   

 Antibiotherapy

      

  Adapted, n (%)

1

(Reference)

0.83

   

  Empirical, n (%)

0.85

0.6–1.22

    

  None, n (%)

0.96

0.5–1.86

    

VAP

1.41

0.98–2.03

0.06

1.60

1.10–2.34

0.017

  1. HSCT haematopoietic stem cell transplantation, G-CSF granulocyte colony-stimulating factors, MV mechanical ventilation, VAP ventilator-associated pneumonia