Table 1 Characteristics of the study population (N = 116)
From: Risks of bleeding and thrombosis in intensive care unit patients with haematological malignancies
Baseline characteristics | ||
 Age | 60 | (48–66) |
 Female | 52 | (45) |
 Diagnosis | ||
  ALL | 15 | (13) |
  AML | 75 | (65) |
  MDS | 26 | (22) |
 Time from leukaemia diagnosis to ICU admission | ||
  Less than 3 months | 35 | (30) |
  3–6 months | 12 | (10) |
  6–12 months | 20 | (17) |
  More than 12 months | 50 | (43) |
 Chemotherapy within 6 weeks prior to admission | 76 | (66) |
 Haematopoietic Stem Cell Transplantation (HSCT) | 43 | (37) |
 Graft-versus-host reaction | 20 | (17) |
 Relapse after having received treatment | 20 | (17) |
 Transformation from other haematological malignancy | 18 | (16) |
  From MDS to AML | 10 | (9) |
  From CML to AML | 2 | (2) |
  From CMML to AML | 2 | (2) |
  From Mb. Waldenstrom to AML | 1 | (1) |
 Respiratory or systemic fungal infection | 19 | (16) |
 Primary reason for ICU admission | ||
  Respiratory failure | 59 | (51) |
  Septic shock/severe sepsis | 39 | (34) |
  Bleeding | 3 | (3) |
  Severe graft-versus-host reaction | 3 | (3) |
  Other | 13 | (11) |
 WBC count at admission (× 109 per litre) | 3 | (0.2–11) |
ICU characteristics | ||
 Sepsisa | 109 | (94) |
  Sepsis | 9 | (8) |
  Severe sepsis | 18 | (15) |
  Septic shock | 82 | (71) |
 Mechanical ventilation in ICU | 101 | (87) |
 Vasopressor in ICU | 95 | (82) |
 Renal replacement therapy in ICU | 42 | (37) |
 Emergency surgery immediately before or during ICU stay | 3 | (3) |
 SAPS II | 58 | (50–75) |
 SOFA (admission) | 12 | (9–14) |
 SOFA (admission) without platelet scoreb | 8 | (6–11) |
 SOFA (maximum) | 14 | (11–17) |
 Length of ICU stay, days | 7 | (2–16) |