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Table 1 Baseline demographics of all patients and those with normal systolic function on day 1

From: Application of updated guidelines on diastolic dysfunction in patients with severe sepsis and septic shock

Variable

All patients (62)

Normal ejection fraction on day 1

N = 44 (71%)

Normal diastolic function (n = 11)

Abnormal diastolic dysfunction (n = 20)

Indeterminate diastolic function (n = 13)

Demographics

 Age

63.1 ± 12.4

55 ± 14

67 ± 8*

62 ± 12

 Sex (M)

35 (56%)

6 (55%)

6 (30%)

6 (46%)

Past medical history

 IHD

19 (31%)

0

3 (15%)

5 (38%)

 Diabetes

20 (32%)

3 (27%)

5 (25%)

4 (31%)

 HTN

37 (60%)

4 (36%)

6 (30%)

6 (46%)

 Previous documented diastolic dysfunction

6 (10%)

0

3 (15%)

2 (15%)

 Previous documented systolic dysfunction

5 (8%)

1 (9%)

0

0

 CRF

11 (18%)

0

5 (25%)

3 (23%)**

Clinical data

 Mechanical ventilation D1 (n)

44 (71%)

7 (64%)

13 (65%)

9 (69%)

 Mechanical ventilation D3

32 (52%)

6 (55%)

8 (40%)

9 (69%)

 Total noradrenaline at first echo (ml)

155 (51, 330)

49 (15, 162)

129 (47, 330)

202 (111,573)

 HR day 1

97 ± 21

97 ± 25

91 ± 17

101 ± 14

 Arrhythmia D1

13 (21%)

2 (18%)

4 (20%)

2 (15%)

 SOFA D1

10 ± 3.7

9.5 ± 4

9.9 ± 3.9

9.1 ± 3.7

 PEEP D1

8 (5, 10)

10 (5, 14)

8 (6, 10)

8 (5,9)

  1. Diastolic dysfunction assessed by 2016 ASE/EACVI guidelines
  2. p values not given unless significant, *p < 0.018; **p < 0.021