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Table 1 Baseline demographics of all patients and those with normal systolic function on day 1

From: Application of updated guidelines on diastolic dysfunction in patients with severe sepsis and septic shock

Variable All patients (62) Normal ejection fraction on day 1
N = 44 (71%)
Normal diastolic function (n = 11) Abnormal diastolic dysfunction (n = 20) Indeterminate diastolic function (n = 13)
Demographics
 Age 63.1 ± 12.4 55 ± 14 67 ± 8* 62 ± 12
 Sex (M) 35 (56%) 6 (55%) 6 (30%) 6 (46%)
Past medical history
 IHD 19 (31%) 0 3 (15%) 5 (38%)
 Diabetes 20 (32%) 3 (27%) 5 (25%) 4 (31%)
 HTN 37 (60%) 4 (36%) 6 (30%) 6 (46%)
 Previous documented diastolic dysfunction 6 (10%) 0 3 (15%) 2 (15%)
 Previous documented systolic dysfunction 5 (8%) 1 (9%) 0 0
 CRF 11 (18%) 0 5 (25%) 3 (23%)**
Clinical data
 Mechanical ventilation D1 (n) 44 (71%) 7 (64%) 13 (65%) 9 (69%)
 Mechanical ventilation D3 32 (52%) 6 (55%) 8 (40%) 9 (69%)
 Total noradrenaline at first echo (ml) 155 (51, 330) 49 (15, 162) 129 (47, 330) 202 (111,573)
 HR day 1 97 ± 21 97 ± 25 91 ± 17 101 ± 14
 Arrhythmia D1 13 (21%) 2 (18%) 4 (20%) 2 (15%)
 SOFA D1 10 ± 3.7 9.5 ± 4 9.9 ± 3.9 9.1 ± 3.7
 PEEP D1 8 (5, 10) 10 (5, 14) 8 (6, 10) 8 (5,9)
  1. Diastolic dysfunction assessed by 2016 ASE/EACVI guidelines
  2. p values not given unless significant, *p < 0.018; **p < 0.021
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