Table 1 Comparison of moderate-severe TBI children with at least one pituitary hormon deficiency to those without deficiency
From: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress
Population | Any Pituitary hormon deficiency | No deficiency | p | |
|---|---|---|---|---|
Number (%) | 110 | 23 (21%) | 87 (79%) | |
Age (years) | 7.8 (2.1–12.5) | 9.4 (7.2–11.7) | 7.38 (6.2–8.5) | Ns |
Male | 73 (66%) | 19 (83%) | 54 (62%) | Ns |
Body weight (kg) | 30 (14–45) | 37.4 (28.4–46.4) | 28.1 (24.1–32) | Ns |
Cause of TBI | Ns | |||
Road Traffic Accident | 56 (51%) | 12 (52%) | 44 (51%) | |
Inflicted | 12 (11%) | 0 | 12 (14%) | |
Fall | 33 (30%) | 10 (44%) | 23 (26%) | |
Blunt I | 7 (6%) | 1 (4%) | 6 (7%) | |
Penetrating | 2 (2%) | 0 | 2 (2%) | |
GCS | 7 (5–9) | 7 (5–8) | 7 (6–7) | Ns |
Pupillary dilatation | 25 (23%) | 3/22 (14%) | 22/85 (26%) | Ns |
ISS | 26 (17–33) | 29 (24–33) | 25 (23–27) | Ns |
PIM2 | 9.2 (3.9–8.7) | 10.2 (3.4–16.9) | 9 (6.6–11.3) | Ns |
PELOD | 16.8 (11–22) | 17.8 (12.2–23.5) | 16.6 (14.4–18.9) | Ns |
Intracranial hypertension | 53 (49%) | 13 (57%) | 40/86 (47%) | Ns |
Neurosurgery | 32 (29%) | 4 (17%) | 28/86 (33%) | Ns |
IV Fluid Bolus | ||||
Day 1 | 71 (65%) | 16 (70%) | 55/86 (64%) | Ns |
Day 2 | 41 (38%) | 15 (65%) | 26/86 (30%) | 0.002 |
Day3 | 19 (18%) | 7 (30%) | 12/85 (14%) | Ns |
Vasoactive drugs | ||||
Day 1 | 34 (31%) | 9 (39%) | 25/86 (29%) | Ns |
Day 2 | 20 (18%) | 6 (26%) | 14/86 (16%) | Ns |
Day 3 | 17 (16%) | 5 (22%) | 12/85 (14%) | Ns |
Hemodynamic instability (until PICU discharge) | ||||
3 (3%) | 0/22 | 3/82 (4%) | Ns | |
PICU stay | 12.4 (4–12) | 9.9 (6.6–13.3) | 13 (6.3–19.8) | Ns |
POPC (PICU discharge) | 3 (2–4) | 3 (2–3) | 2 (2–3) | Ns |
Death (PICU) | 3 (2.7%) | 0 | 3 | |