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Table 3 Ventilatory support data during the study period; data are presented as number (%) or mean (SD)

From: Extracorporeal membrane oxygenation for severe Middle East respiratory syndrome coronavirus

  Day 1 Day 3 Day 7 Day 10 Day 14
ECMO (n = 17) Non-ECMO (n = 18) ECMO (n = 14) Non-ECMO (n = 15) ECMO (n = 14) Non-ECMO (n = 15) ECMO (n = 14) Non-ECMO (n = 15) ECMO (n = 14) Non-ECMO (n = 14)
Invasive ventilation n (%) 17 (100%) 18 (100%) 14 (100%) 16 (100%) 14 (100%) 15 (100%) 11 (78.6%) 14 (93.3%) 5 (35.7%) 13 (92.9%)*
Mode of ventilation
 CMV 6 (35.3%) 10 (55.6%) 7 (50%) 11 (68.8%) 6 (42.8%) 8 (53.3%) 4 (36.4%) 6 (42.9%) 1 (20%) 11 (84.6%)*
 PCV 3 (17.6%) 2 (11.1%) 4 (28.6%) 1 (6.3%) 4 (28.5%) 3 (20%) 3 (27.3%) 5 (35.7%) 3 (60%) 0 (0%)*
 VCV 4 (23.5%) 4 (22.2%) 1 (7.1%) 2 (12.5%) 1 (7.1%) 1 (6.7%) 1 (9.1%) 2 (14.3%) 1 (20%) 0 (0%)
 PRVC 2 (11.8%) 1 (5.6%) 3 (21.4%) 0 (0%) 1 (7.1%) 2 (13.3%) 0 (0%) 1 (7.1%) 0 (0%) 1 (7.7%)
 APRV 1 (6.7%) 1 (5.6%) 1 (7.1%) 0 (0%) 1 (7.1%) 1 (6.7%) 0 (0%) 0 (0%) 0 (0%) 1 (7.7%)
 SIMV 1 (5.9%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (9.1%) 0 (0%) 0 (0%) 0 (0%)
 PSV 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (9.1%) 0 (0%) 0 (0%) 0 (0%)
 CPAP 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (9.1%) 0 (0%) 0 (0%) 0 (0%)
 HFOV 0 (0%) 0 (0%) 0 (0%) 1 (6.3%) 1 (7.1%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
 FiO2 (%) 0.67 (0.29) 0.80 (0.24) 0.59 (0.24) 0.79 (0.25)* 0.50 (0.21) 0.73 (0.24)* 0.50 (0.25) 0.66 (0.27) 0.33 (0.17) 0.72 (0.38)*
 PaO2/FiO2 ratio (%) 115 (110.2) 109 (93.9) 109 (81.51) 63 (62.7) 124 (106.9) 63 (66.1)* 138 (139.5) 36 (66.4)* 237 (42.11) 85 (31.95)*
 PEEP (cm H2O) 12 (3.97) 12 (6.4) 13 (3.94) 14 (4.8) 11 (3.61) 14 (5.6) 11 (4.04) 11 (5.7) 10 (7.20) 13 (7.0)
 Use of NMBs n (%) 8 (53.3%) 12 (66.7%) 10 (76.9%) 12 (80%) 10 (71.4) 8 (53.3%) 4 (36.4%) 3 20%) 2 (40%) 0 (0%)
  1. CMV continuous mandatory ventilation, PCV pressure-controlled ventilation, VCV volume-controlled ventilation, PRVC pressure-regulatory volume control ventilation, APRV airway pressure release ventilation, SIMV synchronised intermittent mandatory ventilation, PSV pressure-support ventilation, CPAP continuous positive airway pressure, HFOV high-frequency oscillatory ventilation, FiO 2 inspired oxygen fraction, PaO 2 /FiO 2 arterial oxygen tension to FiO2 ratio, PEEP positive end-expiratory pressure, ARM alveolar recruitment maneuver, NMBs neuromuscular blocking drugs
  2. *P < 0.05 versus ECMO group