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Table 1 Characteristics of the patients and baseline coagulation parameters

From: Thromboelastography-based anticoagulation management during extracorporeal membrane oxygenation: a safety and feasibility pilot study

Characteristics of the patients

TEG group (N = 21)

aPTT group (N = 21)

P value*

Age (years)

43 (36–53)

48 (40–58)

0.24

Female sex, N (%)

13 (62)

5 (24)

0.03

BMI (kg/m2)

21.8 (20.8–26.1)

27.7 (21.2–29.4)

0.11

ECMO duration (days)

9 (7–16)

11 (4–17)

0.74

Cause of respiratory failure

  

0.73

 ARDS, N (%)

14 (66.7)

16 (76.2)

 

 Bridge to lung transplant, N (%)

6 (28.6)

5 (23.8)

 

 Status asthmaticus, N (%)

1 (4.8)

0

 

Renal replacement therapy, N (%)

4 (19)

7 (33)

0.48

SOFA

7 (5–10)

9 (6–11)

0.54

ICU mortality, N (%)

4 (19)

6 (29)

0.72

Hospital mortality, N (%)

4 (19)

6 (29)

0.72

Baseline coagulation parameters

   

 Platelet count (*109/L)

185 (81–205)

154 (109–268)

0.77

 Hemoglobin (g/L)

10.6 (9–11.1)

11.2 (9.8–12.3)

0.09

 Creatinine (mg/dL)

0.9 (0.4–1.0)

1.1 (08.1.62)

0.20

 Fibrinogen (mg/dL)

520 (350–626)

476 (357–573)

0.77

 PT (ratio)

1.3 (1.2–1.4)

1.3 (1.1–1.5)

0.87

 DIC°, N (%)

1 (4.8)

1 (4.8)

0.76

 DIC score°

1 (1–3)

3 (2–3)

0.33

  1. Data are reported as median (25th–75th percentile) or as absolute and relative frequencies as appropriate
  2. BMI body mass index, ARDS acute respiratory distress syndrome, SOFA sepsis-related organ failure assessment, PT prothrombin time, DIC disseminated intravascular coagulation, ICU intensive care unit
  3. *From Wilcoxon rank-sum (continuous variables) or Fisher’s exact (categorical variables) test
  4. °ISTH criteria (Taylor, FB et al. Thromb Haemost. 2001). DIC patients: #4 (aPTT group) and #30 (TEG group)