Table 3 Univariate analyses
From: Physiological predictors of respiratory and cough assistance needs after extubation
Parameters | No NIV or mechanical cough assistance after extubation (n = 81) | NIV or mechanical cough assistance after extubation | P value* | ||
|---|---|---|---|---|---|
Mean ± SD or n (%) | All patients (n = 44) Mean ± SD or n (%) | Patients who required NIV (n = 36) Mean ± SD or n (%) | Patients who required Mechanical cough assistance (n = 8) Mean ± SD or n (%) | ||
Age, years | 58.8 ± 14.8 | 59.8 ± 16.4 | 59.6 ± 15.7 | 60.8 ± 20.3 | 0.71 |
SOFA at admission | 7.7 ± 5 | 7.2 ± 4.2 | 7.5 ± 4.1 | 5.9 ± 4.8 | 0.59 |
Coma Glasgow Scale score | 15 ± 0 | 15 ± 0 | 15 ± 0 | 15 ± 0 | 1.00 |
Chronic respiratory failure | 11 (14%) | 14 (32%) | 14 (39%) | 0 | 0.015 |
Chronic heart disease | 10 (12%) | 3 (7%) | 3 (8%) | 0 | 0.34 |
Duration of MV, days | 12.7 ± 8.8 | 17.8 ± 15.6 | 17.4 ± 14.4 | 19.8 ± 21.2 | 0.02 |
Diameter of the endotracheal tube, mm | 7.5 ± 0.3 | 7.4 ± 0.3 | 7.3 ± 0.3 | 7.6 ± 0.3 | 0.17 |
MRC score | 51.1 ± 12 | 43 ± 15.5 | 43.2 ± 12.2 | 42.2 ± 12.2 | 0.004 |
Tracheal aspiration before extubation (n/24 h) | 7.8 ± 3 | 7.7 ± 2.7 | 7.7 ± 2.5 | 7.6 ± 3.6 | 0.89 |
Respiratory rate (breaths/min) | 23.2 ± 11.8 | 24.5 ± 5.6 | 24.8 ± 5.9 | 23.4 ± 4.2 | 0.50 |
Borg Scale score (/10) | 1.9 ± 2.3 | 2.1 ± 2.2 | 2 ± 2 | 2.3 ± 3.5 | 0.60 |
PaCO2 before extubation | 5.0 ± 0.6 | 5.6 ± 1 | 5.8 ± 1 | 4.9 ± 0.7 | 0.00007 |
VC (mL) before extubation | 1574 ± 498 | 1281 ± 536 | 1220 ± 513 | 1558 ± 586 | 0.003 |
FVC (mL) before extubation | 1571 ± 520 | 1146 ± 457 | 1121 ± 464 | 1257 ± 439 | 0.00002 |
MIP (cmH2O) before extubation | 37 ± 15 | 31 ± 15 | 32 ± 15 | 26 ± 12 | 0.025 |
MEP (cmH2O) before extubation | 53 ± 28 | 41 ± 24 | 44 ± 25 | 30 ± 16 | 0.021 |
PEF (L/min) before extubation | 80 ± 32 | 62 ± 30 | 60 ± 29 | 71 ± 36 | 0.004 |
PCEF (L/min) before extubation | 97 ± 36 | 72 ± 33 | 71 ± 33 | 75 ± 36 | 0.0003 |
VC (mL) after extubation | 1838 ± 637 | 1364 ± 499 | 1343 ± 511 | 1463 ± 464 | 0.00017 |
FVC (mL) after extubation | 1766 ± 554 | 1284 ± 433 | 1284 ± 440 | 1282 ± 441 | 0.00003 |
MIP (cmH2O) after extubation | 28 ± 13 | 23 ± 11 | 23 ± 11 | 22 ± 10 | 0.07 |
MEP (cmH2O) after extubation | 43 ± 22 | 29 ± 17 | 31 ± 17 | 21 ± 12 | 0.002 |
PEF (L/min) after extubation | 142 ± 77 | 107 ± 63 | 109 ± 66 | 95 ± 47 | 0.02 |
PCEF (L/min) after extubation | 166 ± 76 | 107 ± 66 | 110 ± 72 | 94 ± 39 | 0.0001 |