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Table 3 Univariate analyses

From: Physiological predictors of respiratory and cough assistance needs after extubation

Parameters No NIV or mechanical cough assistance after extubation (n = 81) NIV or mechanical cough assistance after extubation P value*
Mean ± SD or n (%) All patients
(n = 44)
Mean ± SD or n (%)
Patients who required
NIV (n = 36)
Mean ± SD or n (%)
Patients who required
Mechanical cough assistance (n = 8)
Mean ± SD or n (%)
Age, years 58.8 ± 14.8 59.8 ± 16.4 59.6 ± 15.7 60.8 ± 20.3 0.71
SOFA at admission 7.7 ± 5 7.2 ± 4.2 7.5 ± 4.1 5.9 ± 4.8 0.59
Coma Glasgow Scale score 15 ± 0 15 ± 0 15 ± 0 15 ± 0 1.00
Chronic respiratory failure 11 (14%) 14 (32%) 14 (39%) 0 0.015
Chronic heart disease 10 (12%) 3 (7%) 3 (8%) 0 0.34
Duration of MV, days 12.7 ± 8.8 17.8 ± 15.6 17.4 ± 14.4 19.8 ± 21.2 0.02
Diameter of the endotracheal tube, mm 7.5 ± 0.3 7.4 ± 0.3 7.3 ± 0.3 7.6 ± 0.3 0.17
MRC score 51.1 ± 12 43 ± 15.5 43.2 ± 12.2 42.2 ± 12.2 0.004
Tracheal aspiration before extubation (n/24 h) 7.8 ± 3 7.7 ± 2.7 7.7 ± 2.5 7.6 ± 3.6 0.89
Respiratory rate (breaths/min) 23.2 ± 11.8 24.5 ± 5.6 24.8 ± 5.9 23.4 ± 4.2 0.50
Borg Scale score (/10) 1.9 ± 2.3 2.1 ± 2.2 2 ± 2 2.3 ± 3.5 0.60
PaCO2 before extubation 5.0 ± 0.6 5.6 ± 1 5.8 ± 1 4.9 ± 0.7 0.00007
VC (mL) before extubation 1574 ± 498 1281 ± 536 1220 ± 513 1558 ± 586 0.003
FVC (mL) before extubation 1571 ± 520 1146 ± 457 1121 ± 464 1257 ± 439 0.00002
MIP (cmH2O) before extubation 37 ± 15 31 ± 15 32 ± 15 26 ± 12 0.025
MEP (cmH2O) before extubation 53 ± 28 41 ± 24 44 ± 25 30 ± 16 0.021
PEF (L/min) before extubation 80 ± 32 62 ± 30 60 ± 29 71 ± 36 0.004
PCEF (L/min) before extubation 97 ± 36 72 ± 33 71 ± 33 75 ± 36 0.0003
VC (mL) after extubation 1838 ± 637 1364 ± 499 1343 ± 511 1463 ± 464 0.00017
FVC (mL) after extubation 1766 ± 554 1284 ± 433 1284 ± 440 1282 ± 441 0.00003
MIP (cmH2O) after extubation 28 ± 13 23 ± 11 23 ± 11 22 ± 10 0.07
MEP (cmH2O) after extubation 43 ± 22 29 ± 17 31 ± 17 21 ± 12 0.002
PEF (L/min) after extubation 142 ± 77 107 ± 63 109 ± 66 95 ± 47 0.02
PCEF (L/min) after extubation 166 ± 76 107 ± 66 110 ± 72 94 ± 39 0.0001
  1. Italics indicate significant data
  2. SOFA Sequential Organ Failure Assessment, MRC Medical Research Council sum score, PaO 2 partial pressure of O2 in arterial blood, PaCO 2 partial pressure of CO2 in arterial blood, FiO 2 fraction of inspired O2, VC vital capacity, FVC forced vital capacity, MIP maximal inspiratory pressure, MEP maximal expiratory pressure, PEF peak expiratory flow, PCEF peak cough expiratory flow, NS nonsignificant
  3. *P values compare patients with and without NIV and/or mechanical cough assistance