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Table 5 Cost–benefit and sensitivity analysis

From: The effect of a medication reconciliation program in two intensive care units in the Netherlands: a prospective intervention study with a before and after design

Cost–benefit analysis

Calculation

Costs and benefits

Outcomea

1.

Costs of SERVICE (Pharmacist labor)

 

 Admission

−€ 7476

 Discharge

−€ 7256

2.

Cost avoidance

 

 Admission

€ 7911

 Discharge

€ 28,687

3. (= 2–1)

Net cost–benefit

 

 During intervention period

€ 21,868

 Per patient (at admission)

€ 103

4. (= 2:1)

Cost–benefit ratio

2.48

Sensitivity analysis

Variable

Variation

Cost–benefit ratio

Time

+ 50% minutes per intervention

1.66

− 50% minutes per intervention

4.96

Salary

Highest point on hospital pharmacist scale

2.22

Lowest point on hospital pharmacist scale

3.55

Pharmacy technician (7th year)

7.73

ADE probability

− 50%

1.24

50%

3.73

ADE cost

Based on Bates et al. [28]

16.52

  1. ADE adverse drug event
  2. aBased on 2014 Euro cost data