Table 4 Performance of included studies that addressed echocardiography maneuvers, pulse contour analysis or noninvasive cardiac output monitor (NICOM®) to predict fluid responsiveness in spontaneously breathing patients
Author, year | Maneuver | Sens (%) | Spec (%) | PPV (%) | NPV (%) | LR+ | LR− | AUC ± SD or (95% CI) |
|---|---|---|---|---|---|---|---|---|
Lamia, 2007 [21] | SVi-PLR ≥ 12.5% | 77 | 100 | 100 | 78 | 0.23 | 0.95 ± 0.04 | |
Maizel, 2007 [22] | ∆CO > 12% | 63 | 89 | 83 | 73 | 6.00 | 0.40 | 0.89 ± 0.06 |
∆SV > 12% | 69 | 89 | 85 | 76 | 6.00 | 0.40 | 0.90 ± 0.06 | |
Biais, 2009 [23] | ∆SV-PLRTE > 13% | 100 | 80 | 91 | 100 | 5.00 | 0.96 ± 0.03 | |
∆SV-PLRFloT > 16% | 85 | 90 | 94 | 75 | 8.50 | 0.17 | 0.92 ± 0.05 | |
Muller, 2012 [24] | cIVC = 40% | 70 | 80 | 72 | 83 | 3.50 | 0.37 | 0.77 (0.60–0.88) |
E wave velocity of 0.7 | 67 | 90 | 84 | 83 | 6.67 | 0.37 | 0.83 (0.68–0.93) | |
Brun, 2013 [25] | ∆VTI-PLR > 12% | 75 | 100 | 100 | 79 | 0.25 | 0.93 (0.83–1.00) | |
VTI ≤ 21 cm | 67 | 100 | 100 | 75 | 0.33 | 0.82 (0.64–1.00) | ||
Lanspa, 2013 [26] | cIVC ≥ 15% | 100 | 67 | 62 | 100 | 3.00 | 0.83 (0.58–1.00) | |
∆SV ≥ 17% | 60 | 100 | 100 | 82 | 0.40 | 0.92 (0.73–1.00) | ||
AoVV ≥ 25% | 75 | 67 | 50 | 85 | 2.25 | 0.37 | 0.67 (0.32–1.00) | |
Airapetian, 2015 [27] | cIVC > 42% | 31 | 97 | 90 | 60 | 9.31 | 0.71 | 0.62 (0.66–0.88) |
IVCmax < 2.1 cm | 93 | 33 | 57 | 83 | 1.40 | 0.21 | 0.62 (0.49–0.75) | |
ΔCO-PLR > 10% | 52 | 87 | 79 | 65 | 3.88 | 0.56 | 0.78 (0.66–0.88) | |
Duus, 2015 [29] | ∆SV-PLR | 80 | 61 | 79 | 65 | 2.09 | 0.31 | 0.74 (0.65–0.83) |
Corl, 2017 [28] | cIVC of 25% | 87 | 81 | 81 | 87 | 4.56 | 0.16 | 0.84 (0.77–0.90) |