Plasma microRNAs levels are different between pulmonary and extrapulmonary ARDS patients: a clinical observational study

Annals of Intensive Care

Table 3 Comparison of patient’s clinical condition indexes between ARDSp and ARDSexp

Variable	Total (n = 57)	ARDS_p(1) (n = 43)	ARDS_exp(2) (n = 14)	P value (1) versus (2)
Lung injury severity
PH	7.4 [7.35–7.45]	7.41 [7.36–7.46]	7.37 [7.32–7.43]	0.26
FiO₂	0.5 [0.4–0.6]	0.5 [0.4–0.6]	0.4 [0.4–0.5]	0.06
PEEP(cmH2O)	8 [5–12]	8 [5–12]	5 [5–12]	0.54
PO₂/FiO₂(mmHg)	165 [112–211]	145 [110–203]	206 [184–253]	0.012
Murray score	2.3 [1.7–3.1]	2.7 [2–3.3]	1.8 [1.3–2.4]	0.008
Infection index
Leukocyte count	10.4 [6–16.7]	10.4 [6.4–14.5]	11.8 [5.5–18.3]	0.81
Platelet count	134 [90–188]	134 [107–195]	128 [49–184]	0.38
CRP	74 [25–128]	74 [31–121]	75 [15–141]	0.87
PCT	1.3 [0.2–12.9]	1. 0 [0.2–13.1]	1.86 [0.7–10.4]	0.60
Shock index
HR	73 [63–121]	72 [63–120]	76 [63–125]	0.66
NE	5 [0–27.5]	4 [0–20]	5 [0–85]	0.21
Lactic acid	2.1 [1–3.1]	2.0 [0.9–2.9]	2.2[1.2–5.4]	0.11
Organ supporting
IMV n (%)	40 (70.2%)	32 (74.4%)	8 (57.1%)	0.37
ECMO n (%)	12 (21.1%)	12 (27.9%)	0 (0%)	0.065
CRRT n (%)	10 (17.5%)	7 (16.3%)	3 (21.4%)	0.97

PH arterial blood pH value, PO₂ arterial partial pressure of oxygen, FiO₂ oxygen concentration, PEEP positive end expiratory pressure, Murray score lung injury score used for ARDS patients, CRP C reactive protein, PCT procalcitonin, IMV invasive mechanical ventilation, ECMO extracorporeal membrane oxygenation, CRRT continuous renal replacement therapy, HR heart rate, NE norepinephrine. P < 0.05 suggests statistical difference