Acute kidney injury epidemiology, risk factors, and outcomes in critically ill patients 16–25 years of age treated in an adult intensive care unit

Annals of Intensive Care

Table 3 Multivariable logistic regression of interactions between age groups and risk factors associated with AKI

Interaction of age group with	χ² (df)	p value*
Race	5.19 (6)	0.52
Diabetes	4.31 (3)	0.22
Cardiac disease	17.55 (3)	< 0.01
Chronic kidney disease	4.67 (3)	0.19
Surgical admission	18.42 (3)	< 0.01
Vasopressor use	1.73 (3)	0.62
Mechanical ventilation	4.57 (3)	0.20
Moderate anemia	2.02 (3)	0.56
APACHE III score	7.07 (3)	0.06
eGFR	16.5 (3)	< 0.01
Hypotensive Index	2.25 (3)	0.52
Vancomycin	1.06 (3)	0.78
Calcineurin inhibitor	12.84 (3)	< 0.01
NSAID	3.30 (3)	< 0.01
Other nephrotoxic medications	8.08 (3)	0.04

AKI acute kidney injury, APACHE Acute Physiology and Chronic Healthy Evaluation, eGFR estimated glomerular filtration rate, NSAID nonsteroidal anti-inflammatory drug
*Each p value comes from a different multivariable logistic regression with age group, 15 risk factors and one interaction