Skip to main content

Table 3 Results of multivariable analyses

From: Predictors of response to fixed-dose vasopressin in adult patients with septic shock

Outcome OR (95% CI) P value
Multivariable analysis and association with response to vasopressina
 Non-medical ICU 1.70 (1.18–2.46) 0.005
 Lactate at AVP initiation, mmol/L 0.93 (0.89–0.97) < 0.001
Multivariable analysis and association with ICU mortality
 Hemodynamic response to AVP 0.51 (0.35–0.76) 0.001
 Catecholamine dose, mcg/kg/min 3.14 (1.36–7.28) 0.008
 Lactate at AVP initiation, mmol/L 1.10 (1.04–1.18) 0.002
 AKI presence
 Rifle versus no AKI 3.64 (1.77–7.49) < 0.001
 Injury versus no AKI 5.80 (1.13–29.60) 0.035
 Failure versus no AKI 2.63 (1.38–5.01) 0.003
 ESRD versus no AKI 2.37 (1.27–4.43) 0.007
 APACHE III score 1.01 (1.01–1.02) < 0.001
 SOFA score 1.16 (1.08–1.25) < 0.001
 Medical ICU 1.58 (1.02–2.45) 0.040
 Race (Caucasian) 1.72 (1.14–2.60) 0.010
 Age 1.01 (1.00–1.03) 0.036
 Hepatic failure 0.89 (0.48–1.62) 0.696
  1. AKI acute kidney injury, AVP vasopressin, ESRD end-stage renal dysfunction, SOFA sequential organ failure assessment
  2. aVariables entered into the model but without a statistically significant association with vasopressin response include RIFLE-defined AKI category, corticosteroid use, SOFA score, APACHE III score, hepatic failure, race, age, and catecholamine dosage (in mcg/kg/min)
\