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Table 2 Plasma cytokines levels from healthy children and children with septic shock

From: Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study

 

Healthy controls

Children with septic shock

Day 1–2

Day 3–5

Day 7–9

IL-6

0.0 [0.0–0.36]

178.5 [25.77–3311]

18.13 [12.92–172.5]

17.97 [3.30–33.08]

IL-8

2.05 [0.43–5.06]

51.72 [19.07–145.7]

21.45 [11.42–56.36]

15.00 [7.98–37.98]

IL-10

0.36 [0.0–4.44]

43.37 [17.11–331.6]

8.26 [3.44–21.66]

11.83 [1.70–23.73]

IL1-RA

0.0 [0.0–17.16]

136.9 [23.72–647.8]

48.02 [0.0–153.2]

56.54 [0.0–121.3]

TNF-α

4.91 [3.35–7.11]

25.13 [14.52–40.47]

8.37 [5.34–14.62]

10.15 [4.10–15.43]

INF-γ

4.98 [1.82–6.45]

15.81 [6.55–24.22]

8.07 [2.78–11.45]

10.92 [4.65–23.70]

  1. Values (pg/ml) are expressed as median [IQR]. All cytokine values in children with septic shock at all-time points were different from those of healthy controls