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Table 3 mHLA-DR and lymphocytes subsets depending on age in healthy and septic children

From: Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study

 

0–2 years

2–8 years

> 8 years

Healthy (n = 11)

Septic (n = 11)

Healthy (n = 14)

Septic (n = 6)

Healthy (n = 5)

Septic (n = 2)

mHLA-DR (ABC)

25,477 [20,478–39,143]

6302 [2187–9278]

34,295 [25,763–43,368]

5913 [2977–8911]

29,597 [26,636–41,939]

7927 [6888–8965]

Total lymphocytes (absolute count; cells/µl)

5934 [4148–8572]

2736 [1962–3550]

3623 [2940–4358]

1680 [897–2453]

2374 [1831–3298]

1047 [403–1691]

CD4+ T cells (absolute count; cells/µl)

2187 [1566–2738]

1186 [939–1640]

1184 [968–1583]

574 [236–478]

895 [682–1100]

332 [187–478]

CD8+ T cells (absolute count; cells/µl)

1033 [910–1380]

487 [311–591]

758 [631–1264]

365 [155–608]

689 [467–924]

161 [51–270]

NK cells (absolute count; cells/µl)

645 [392–753]

58 [25–124]

424 [295–576]

96 [35–156]

315 [191–645]

60 [4–117]

B cells (absolute count; cells/µl)

1811 [1326–2750]

901 [648–1397]

729 [563–988]

622 [288–791]

352 [273–508]

422 [150–693]

Regulatory T cells (% among CD4+)

7.67 [5.39–8.24]

7.72 [5.1–9.0]

6.29 [5.29–8.31]

8.83 [7.1–10.3]

6.80 [6.10–8.48]

7.9 [5.8–10.1]

  1. Values are expressed as median [IQR] according to age group. Septic children values were obtained at day 3