From: Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study
 | 0–2 years | 2–8 years | > 8 years | |||
---|---|---|---|---|---|---|
Healthy (n = 11) | Septic (n = 11) | Healthy (n = 14) | Septic (n = 6) | Healthy (n = 5) | Septic (n = 2) | |
mHLA-DR (ABC) | 25,477 [20,478–39,143] | 6302 [2187–9278] | 34,295 [25,763–43,368] | 5913 [2977–8911] | 29,597 [26,636–41,939] | 7927 [6888–8965] |
Total lymphocytes (absolute count; cells/µl) | 5934 [4148–8572] | 2736 [1962–3550] | 3623 [2940–4358] | 1680 [897–2453] | 2374 [1831–3298] | 1047 [403–1691] |
CD4+ T cells (absolute count; cells/µl) | 2187 [1566–2738] | 1186 [939–1640] | 1184 [968–1583] | 574 [236–478] | 895 [682–1100] | 332 [187–478] |
CD8+ T cells (absolute count; cells/µl) | 1033 [910–1380] | 487 [311–591] | 758 [631–1264] | 365 [155–608] | 689 [467–924] | 161 [51–270] |
NK cells (absolute count; cells/µl) | 645 [392–753] | 58 [25–124] | 424 [295–576] | 96 [35–156] | 315 [191–645] | 60 [4–117] |
B cells (absolute count; cells/µl) | 1811 [1326–2750] | 901 [648–1397] | 729 [563–988] | 622 [288–791] | 352 [273–508] | 422 [150–693] |
Regulatory T cells (% among CD4+) | 7.67 [5.39–8.24] | 7.72 [5.1–9.0] | 6.29 [5.29–8.31] | 8.83 [7.1–10.3] | 6.80 [6.10–8.48] | 7.9 [5.8–10.1] |