| Odds ratio (95% CI) | p value |
---|---|---|
Clinical characteristics and comorbidities | Â | Â |
Age | 1.03 (1.01–1.04) | 0.001 |
Functional status | Â | Â |
 Independent | 1 (Reference) |  |
 Partially dependent | 2.18 (1.31–3.63) | 0.003 |
 Totally dependent | 2.04 (0.83–5.03) | 0.120 |
Hypertension | 1.00 (0.63–1.59) | 0.984 |
Heart failure | 0.96 (0.57–1.63) | 0.888 |
Chronic kidney disease | 1.04 (0.56–1.91) | 0.904 |
COPD | 1.67 (0.93–3.00) | 0.086 |
Immunosuppression | 4.21 (2.12–8.36) | < 0.001 |
Severity of illness | Â | Â |
Non-pulmonary SOFA | 1.14 (1.07–1.22) | < 0.001 |
LIPS | 1.10 (1.02–1.20) | 0.019 |
Management | Â | Â |
Use of NIV before intubation | 1.09 (0.52–2.29) | 0.824 |
Maximum airway pressure (cm H2O) | 1.05 (1.01–1.10) | 0.020 |
PEEP (cm H2O) | 0.93 (0.83–1.04) | 0.200 |
FiO2 | 1.00 (0.99–1.01) | 0.817 |
Laboratory parameters | Â | Â |
PaO2/FiO2 (mmHg) | 1.00 (0.99–1.01) | 0.247 |
PaCO2 (mmHg) | 0.99 (0.98–1.01) | 0.886 |
Acidosis | Â | Â |
 No | 1 (Reference) |  |
 Respiratory | 1.35 (0.66–2.79) | 0.412 |
 Metabolic/Mixed | 1.26 (0.76–2.10) | 0.369 |
Vital signs | Â | Â |
SpO2 (%) | 0.95 (0.91–0.99) | 0.027 |
Heart rate (bpm) | 1.01 (1.00–1.02) | 0.020 |
Mean arterial pressure (mmHg) | 0.99 (0.98–1.00) | 0.153 |