De-escalation of antifungal treatment in critically ill patients with suspected invasive Candida infection: incidence, associated factors, and safety

Annals of Intensive Care

Table 3 Impact of de-escalation on outcome

Characteristics	De-escalation		p
Characteristics	Yes (n = 38)	No (n = 152)	p
Length of ICU stay	25 [14–40]	25 [14–40]	0.99
Duration of mechanical ventilation	22 [5–31]	20 [10–35]	0.43
Total duration of antifungal treatment	6 [5–18]	13 [7–25]	0.023
ICU mortality	17 (45)	89 (59)	0.13
30-day mortality	9 (24)	56 (37)	0.13
1-year mortality	21 (55)	97 (64)	0.33