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Table 2 Comparison of skin laser Doppler (SLD) variables between volunteers and patients and between survivors and non-survivors

From: Skin microcirculatory reactivity assessed using a thermal challenge is decreased in patients with circulatory shock and associated with outcome

SLD variable

Healthy volunteers and initial cohort

Initial cohort

Confirmatory cohort

Volunteers (n = 18)

Patients (n = 29)

P

Survivors (n = 18)

Non-survivors (n = 11)

P

Survivors (n = 17)

Non-survivors (n = 18)

P

Skin blood flow 37 °C (PU)

10.3 (8.0–14.2)

13.0 (10.1–19.5)

0.16

13.4 (10.0–21.6)

13.0 (10.1–19.5)

0.44

12.4 (8.0–17.3)

15.0 (10.2–19.3)

0.44

Skin blood flow 43 °C (PU)

112.8 (88.0–150.0)

36.4 (25.6–76.9)

< 0.01

51.8 (25.6–77.2)

33.7 (16.5–39.0)

0.76

57.4 (41.5–71.5)

33.1 (21.8–41.6)

< 0.01

Skin blood flow ratio

11.2 (9.4–13.4)

2.6 (2.0–3.6)

< 0.01

3.2 (2.2–6.2)

2.3 (1.7–2.8)

< 0.01

3.7 (2.9–6.2)

2.1 (1.6–2.5)

< 0.01

  1. PU perfusion units