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Table 2 Overview of half-life (T1/2) of Ringer’s, glucose and colloid solutions as reported in different studies.

From: Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy

Category

Study population

n

Fluid studied

T1/2 (min)

Volunteers

Healthy adults

24

Glucose 2.5%

19

 

Healthy adults

9

Glucose 5%

13

 

Healthy adults

6

Ringer’s acetate

22–46

 

Healthy adults

8

dextran 70

175

 

Healthy adults

15

Plasma

197

 

Healthy adults

15

Albumin 5%

110

 

Healthy adults

20

HES 130/0.4

110

 

Dehydrated adults

20

Ringer’s acetate

76

 

Healthy children

14

Ringer’s lactate

30

Pregnancy

Normal

8

Ringer’s acetate

71

 

Pre-eclampsia

8

Ringer’s acetate

12

 

Before caesarean section

10

Ringer’s acetate

175

Surgery

Before surgery

29

Ringer’s acetate

23

 

Before surgery

15

Ringer’s lactate

169

 

Thyroid

29

Ringer’s acetate

327–345

 

Laparoscopic cholecystectomy

12

Glucose 2.5%

492

 

Laparoscopic cholecystectomy

12

Ringer’s acetate

268

 

Gynaecological laparoscopy

20

Ringer’s lactate

346

 

Open abdominal

10

Ringer’s lactate

172

 

After hysterectomy

15

Glucose 2.5%

14

 

After laparoscopy

20

Ringer’s lactate

17

  1. HES hydroxyethyl starch