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Table 2 Biochemical characteristics throughout protocol in rabbits presenting experimental acute respiratory distress syndrome and treated by gaseous lung protective ventilation (LPV) or total liquid ventilation (TLV), respectively

From: Hypothermic total liquid ventilation after experimental aspiration-associated acute respiratory distress syndrome

Parameters and groups Baseline Conventional ventilation (t = 90 min) LPV or TLV
30 min 120 min
Arterial blood saturation (%)
LPV 100 ± 0 76 ± 4 62 ± 9 80 ± 5
TLV 100 ± 0 73 ± 3 83 ± 12 90 ± 2
Arterial blood pH
LPV 7.36 ± 0.03 7.15 ± 0.06 7.14 ± 0.15 7.18 ± 0.05
TLV 7.35 ± 0.04 7.22 ± 0.02 7.17 ± 0.04 7.16 ± 0.04
Arterial blood PaO 2 (mmHg)
LPV 227 ± 29 41 ± 5 62 ± 9 52 ± 8
TLV 219 ± 38 51 ± 9 83 ± 12 62 ± 4
Arterial blood PaO 2 /FiO 2 (mmHg)
LPV 755 ± 97 41 ± 5 62 ± 9 52 ± 8
TLV 730 ± 150 51 ± 9 83 ± 12 62 ± 4
Arterial blood PaCO 2 (mmHg)
LPV 47 ± 3 70 ± 11 68 ± 7 67 ± 7
TLV 49 ± 6 72 ± 4 80 ± 5 79 ± 4
Bicarbonate blood level (mmol/l)
LPV 28 ± 2 24 ± 2 23 ± 1 24 ± 2
TLV 28 ± 1 29 ± 2 30 ± 1* 31 ± 2*
  1. Statistical comparisons were only made for group effect but not among time points
  2. n = 8 in each LPV and TLV group; Fi02, inhaled fraction of oxygen
  3. *p < 0.05 versus LPV