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Table 2 Mean estimates of iron parameters derived from the linear mixed model

From: Iron metabolism in critically ill patients developing anemia of inflammation: a case control study

Iron parameter

AI

Septic controls, high Hb

Non-septic controls, high Hb

Iron (µmol/L)

3.8 (3.2–4.5)*†

5.6 (4.8–6.6)

6.3 (5.4–7.3)

Transferrin (g/L)

1.3 (1.2–1.5)*†

1.6 (1.5–1.8)

1.9 (1.7–2)

Transferrin saturation (%)

10 (8–12)*

14 (11–16)

13 (11–15)

Ferritin (µg/L)

1134 (548–2346)†

473 (229–976)

314 (152–648)

Haptoglobin (g/L)

3.5 (3.2–3.9)*†

2.7 (2.4–3)

2.5 (2.2–2.8)

Hepcidin (pg/ml)

20.7 (15.1–28.5)†

12.9 (9.4–17.9)

7.3 (5.4–9.8)

Erythroferrone (pg/ml)

15.5 (9.3–26)

9.6 (5.8–16)

18.7 (11.2–31)

sTfR (µg/ml)

0.83 (0.68–1.01)

0.7 (0.55–0.87)

0.70 (0.57–0.86)

IL-6 (pg/ml)

14.4 (5.1–40.9)†

8.0 (1.5–43.0)

2.0 (0.4–10.9)

  1. Data are expressed as (back-transformed) mean estimates of iron parameters for all patients per group at all time points, with 95% confidence interval
  2. Differences between mean estimates are tested by contrasts. * p < 0.05 AI compared to septic controls, † p < 0.05 AI compared to non-septic controls