|
Male gender (n, %)
|
97
|
64 (66)
|
50 (65.8)
|
14 (66.7)
|
1
|
|
Age (years, n)
|
97
|
67 [46–75]
|
64 [44–73]
|
71 [56–81]
|
0.034
|
|
APACHE II (pts)
|
97
|
16 ± 7
|
14 ± 7
|
22 ± 6
|
< 0.001
|
|
SOFA (pts)
|
97
|
7 [4–10]
|
6 [4–9]
|
12 [8–15]
|
< 0.001
|
|
ICU admission diagnosis, n (%)
|
97
| | | |
0.046
|
| | |
Trauma 37 (38.1)
|
34
|
3(8.1)
| |
| | |
Neurologic 21 (21.6)
|
17
|
4(19)
| |
| | |
Respiratory 11 (11.3)
|
8
|
3(27.3)
| |
| | |
Sepsis 9 (9.3)
|
6
|
3 (33.3)
| |
| | |
Other 19 (19.7)
|
11
|
8(42.1)
| |
|
Heart rate (bpm)
|
97
|
79 [61–102]
|
77 [61–95]
|
96 [69–107]
|
0.045
|
|
Mean arterial pressure (mmHg)
|
97
|
84 ± 19
|
86 ± 17
|
79 ± 27
|
0.255
|
|
Vasoactive drugs (treated)
|
54
| |
38(50)
|
16(76.2)
|
0.046
|
|
Noradrenaline (mcg/kg/min)
|
52
|
0.28 [0.14–0.61]
| | | |
|
Dopamine (mcg/kg/min)
|
5
|
6.1 [4.8–7.4]
| | | |
|
Dobutamine (mcg/kg/min)
|
8
|
2.54 [2–4.5]
| | | |
|
Cumulative Vasopressor Index
|
54
|
4 [4]
|
1 [0–4]
|
4 [2–4]
|
0.008
|
|
Glasgow Coma Scale (pts)
|
97
|
10 [3–15]
|
10 [4–15]
|
4 [3–14]
|
0.074
|
|
Mechanical ventilation (n, %)
|
97
|
91 (93.8)
|
71(93.4)
|
21(100)
|
0.581
|
|
Peep (cmH2O)
|
91
|
7 [6–9]
|
7 [6–9]
|
8 [7–10]
|
0.095
|
|
Haemoglobin (g/dL)
|
97
|
11 ± 1.78
|
11.1 ± 1.7
|
10.8 ± 2.2
|
0.58
|
|
White blood cells (n × 103/mmc)
|
97
|
12.1 [8.83–14.81]
|
11.3 [8.8–15.7]
|
12.7 [9.5–14.6]
|
0.518
|
|
Platelets (n × 103/mmc)
|
97
|
150 [102–199]
|
165 [110–201]
|
115 [56–173]
|
0.02
|
|
Creatinine (mg/dL)
|
97
|
1.0 [0.8–1.45]
|
1 [0.8–1.2]
|
1.4 [1.1–1.8]
|
< 0.001
|
|
Bilirubine (mg/dL)
|
97
|
0.8 [0.5–1.2]
|
0.75 [0.5–1.1]
|
0.9 [0.4–1.8]
|
0.264
|
|
PaO2 (mmHg)
|
97
|
146 [104–175]
|
147 [106–176]
|
140 [93–172]
|
0.63
|
|
Arterial lactates (mmol/L)
|
97
|
1.4 [1.0–2.15]
|
1.3 [0.9–1.67]
|
3.1 [1.4–5.6]
|
< 0.001
|
|
ScvO2 (%)
|
60
|
77.2 [71–82.3]
|
77.7 [72.3–82.5]
|
75.6 [62.7–80.8]
|
0.24
|
|
Microcirculatory variables
| | | | | |
|
TVD (small) (mm/mm2)
|
97
|
20.4 ± 3.7
|
20.5 [17.2–22.7]
|
20.9 [17.8–22.7]
|
0.817
|
|
PVD (small) (mm/mm2)
|
97
|
19.3 ± 4.4
|
19.3 ± 4
|
19.3 ± 6
|
0.951
|
|
De Backer score (small) (n/mm)
|
97
|
11.9 ± 2
|
11.8 ± 2
|
12.2 ± 2
|
0.489
|
|
PPV (small) (%)
|
97
|
98.3 [95.4–100]
|
98.2 [94.8–100]
|
98.3 [97–100]
|
0.688
|
|
MFI (small) (AU)
|
97
|
3 [2.7–3.0]
|
3 [2.75–3]
|
2.93 [2.3–3]
|
0.155
|
|
HI (small)
|
97
|
0 [0.0–0.2]
|
0 [0–0.2]
|
0 [0–0.3]
|
0.417
|
|
Abnormal MFI (n, %)
|
97
|
20 (20.6)
|
11 (14.5)
|
9 (42.9)
|
0.012
|
