Skip to main content
Annals of Intensive Care

Table 3 Systemic and cerebral hemodynamics in patients responders–responders (RR) versus responders–non-responders (RnR) in the sepsis group

From: Impact of fluid challenge increase in cardiac output on the relationship between systemic and cerebral hemodynamics in severe sepsis compared to brain injury and controls

 

RR

n = 23

RNR

n = 15

p

Baseline

 CO (l min−1)

5.7 (4 to 6.8)

4.9 (3.5 to 6.7)

0.4288

 SV (ml)

54 (38 to 71)

52 (41 to 75)

0.8076

 HR (min−1)

108 (89 to 124)

93 (71 to 101)

0.0374

 SAP (mmHg)

99 (88 to 110)

107 (86 to 121)

0.2382

 DAP (mmHg)

51 (44 to 58)

53 (50 to 57)

0.5107

 MAP (mmHg)

64 56 to 74)

70 (62 to 77)

0.1685

 PP (mmHg)

45 (34 to 60)

49 (42 to 69)

0.2382

 PSV (cm s−1)

81 (63 to 108)

101 (82 to 107)

0.5205

 EDV (cm s−1)

36 (25 to 42)

33 (26 to 36)

0.4287

FC test

 ∆CO (%)

27 (18 to 35)*

27 (14 to 29)*

0.3323

 ∆SV (%)

39 (20 to 44)*

25 (14 to 29)*

0.0993

 ∆HR (%)

− 5 (− 9 to 0)*

− 2 (− 4 to 3)

0.0928

 ∆SAP (%)

30 (14 to 39)*

1 (− 1 to 5)

< 0.0001

 ∆DAP (%)

12 (7 to 18)*

0 (− 4 to 3)

< 0.0001

 ∆MAP (%)

25 (13 to 29)*

0 (− 4 to 4)

< 0.0001

 ∆PP (%)

52 (22 to 67)*

4 (− 1 to 14)

< 0.0001

 ∆PSV (%)

24 (11 to 30)*

10 (− 2 to 33)*

0.1348

 ∆EDV (%)

17 (14 to 42)*

18 (5 to 42)*

0.7400

  1. Quantitative values were expressed as median (25th–75th). Statistical tests: intragroup: nonparametric Wilcoxon test; intergroup: nonparametric Mann–Whitney test
  2. CO cardiac output, SV stroke volume, HR heart rate, SAP systolic arterial pressure, DAP diastolic arterial pressure, MAP mean arterial pressure, PP pulse pressure, PSV pic systolic velocity, EDV end diastolic velocity, FC fluid challenge, RR responders responders, RNR responders non-responders
  3. *Significant difference after FL compared with baseline
Back to article page