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Table 3 Systemic and cerebral hemodynamics in patients responders–responders (RR) versus responders–non-responders (RnR) in the sepsis group

From: Impact of fluid challenge increase in cardiac output on the relationship between systemic and cerebral hemodynamics in severe sepsis compared to brain injury and controls

  RR
n = 23
RNR
n = 15
p
Baseline
 CO (l min−1) 5.7 (4 to 6.8) 4.9 (3.5 to 6.7) 0.4288
 SV (ml) 54 (38 to 71) 52 (41 to 75) 0.8076
 HR (min−1) 108 (89 to 124) 93 (71 to 101) 0.0374
 SAP (mmHg) 99 (88 to 110) 107 (86 to 121) 0.2382
 DAP (mmHg) 51 (44 to 58) 53 (50 to 57) 0.5107
 MAP (mmHg) 64 56 to 74) 70 (62 to 77) 0.1685
 PP (mmHg) 45 (34 to 60) 49 (42 to 69) 0.2382
 PSV (cm s−1) 81 (63 to 108) 101 (82 to 107) 0.5205
 EDV (cm s−1) 36 (25 to 42) 33 (26 to 36) 0.4287
FC test
 ∆CO (%) 27 (18 to 35)* 27 (14 to 29)* 0.3323
 ∆SV (%) 39 (20 to 44)* 25 (14 to 29)* 0.0993
 ∆HR (%) − 5 (− 9 to 0)* − 2 (− 4 to 3) 0.0928
 ∆SAP (%) 30 (14 to 39)* 1 (− 1 to 5) < 0.0001
 ∆DAP (%) 12 (7 to 18)* 0 (− 4 to 3) < 0.0001
 ∆MAP (%) 25 (13 to 29)* 0 (− 4 to 4) < 0.0001
 ∆PP (%) 52 (22 to 67)* 4 (− 1 to 14) < 0.0001
 ∆PSV (%) 24 (11 to 30)* 10 (− 2 to 33)* 0.1348
 ∆EDV (%) 17 (14 to 42)* 18 (5 to 42)* 0.7400
  1. Quantitative values were expressed as median (25th–75th). Statistical tests: intragroup: nonparametric Wilcoxon test; intergroup: nonparametric Mann–Whitney test
  2. CO cardiac output, SV stroke volume, HR heart rate, SAP systolic arterial pressure, DAP diastolic arterial pressure, MAP mean arterial pressure, PP pulse pressure, PSV pic systolic velocity, EDV end diastolic velocity, FC fluid challenge, RR responders responders, RNR responders non-responders
  3. *Significant difference after FL compared with baseline
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