Table 1 Characteristics of hypoxemic patients according to severity of hypoxemia
From: Hypoxemia in the ICU: prevalence, treatment, and outcome
All hypoxemic patients, n = 859 | Mild hypoxemia P/F 201–300 mmHg, n = 440 | Moderate hypoxemia P/F 101–200 mmHg, n = 345 | Severe hypoxemia P/F ≤ 100 mmHg, n = 74 | p | |
|---|---|---|---|---|---|
Age, years median (IQR) | 64 [53–73] | 65 [54–74] | 65 [53–73] | 58 [47–69] | 0.006 |
Female, N (%) | 273 (31.8) | 142 (32.3) | 109 (31.6) | 22 (29.7) | 0.91 |
Body mass index (n = 844/431/341/72) | 26.1 [22.5–31.1] | 26.1 [22.7–30.9] | 26.0 [22.5–31.0] | 27.0 [22.1–34.4] | 0.83 |
Main diagnosis at ICU admission (n = 858/439/345/74) | – | ||||
Septic shock | 124 (14.5) | 67 (15.2) | 49 (14.2) | 8 (10.8) | |
Other shock | 47 (5.5) | 24 (5.4) | 17 (4.9) | 6 (8.1) | |
Severe trauma | 20 (2.3) | 14 (3.2) | 6 (1.7) | 0 (0) | |
De novo acute respiratory failure | 275 (32.0) | 118 (26.9) | 120 (34.8) | 37 (50.0) | |
Acute on chronic respiratory failure | 128 (14.9) | 55 (12.5) | 68 (19.7) | 5 (6.8) | |
Coma/seizures | 66 (7.7) | 43 (9.8) | 19 (5.5) | 4 (5.4) | |
Metabolic disorders | 18 (2.1) | 11 (2.5) | 6 (1.7) | 1 (1.4) | |
Hepatic failure | 6 (0.7) | 2 (0.5) | 2 (0.6) | 2 (2.7) | |
Cardiac arrest | 30 (3.5) | 15 (3.4) | 12 (3.5) | 3 (4.1) | |
Postoperative surveillance | 96 (11.2) | 64 (14.6) | 31 (9.0) | 1 (1.3) | |
Other | 48 (5.6) | 26 (5.9) | 15 (4.4) | 7 (9.5) | |
Admission category (n = 857/439/344/74) | 0.004 | ||||
Medical | 675 (78.8) | 327 (74.5) | 281 (81.7) | 67 (90.5) | |
Scheduled surgery | 76 (8.9) | 49 (11.1) | 27 (7.8) | 0 (0) | |
Urgent surgery | 92 (10.7) | 53 (12.1) | 32 (9.3) | 7 (9.5) | |
Trauma | 14 (1.6) | 10 (2.3) | 4 (1.2) | 0 (0) | |
SAPS II (n = 832/425/334/73) | 43 [31–57] | 42 [30–56] | 43 [31–57] | 45 [34–61] | 0.32 |
Chronic respiratory disease (obstructive) (n = 855/440/342/73) | 288 (33.7) | 141 (32.1) | 127 (37.1) | 20 (27.4) | 0.16 |
Chronic respiratory disease (restrictive) (n = 855/440/342/73) | 71 (8.3) | 28 (6.4) | 37 (10.8) | 6 (8.2) | 0.08 |
Obstructive sleep apnea syndrome (n = 855/440/342/73) | 71 (8.3) | 36 (8.2) | 29 (8.5) | 6 (8.2) | 0.99 |
Chronic oxygen therapy (n = 855/440/342/73) | 71 (8.3) | 32 (7.3) | 33 (9.7) | 6 (8.2) | 0.49 |
Long-term non-invasive ventilation (n = 855/440/342/73) | 32 (3.7) | 17 (3.9) | 14 (4.1) | 1 (1.4) | 0.68 |
Chronic heart failure (n = 855/440/342/73) | 145 (17.0) | 74 (16.8) | 62 (18.1) | 9 (12.3) | 0.48 |
Chronic kidney failure (n = 855/440/342/73) | 83 (9.7) | 55 (12.5) | 23 (6.7) | 5 (6.9) | 0.02 |
Cirrhosis (n = 855/440/342/73) | 45 (5.3) | 25 (5.7) | 15 (4.4) | 5 (6.9) | 0.54 |
Cancer (n = 855/440/342/73) | 79 (9.2) | 43 (9.8) | 32 (9.4) | 4 (5.5) | 0.50 |
Immunosuppression (n = 853/439/341/73) | 99 (11.6) | 46 (10.5) | 43 (12.6) | 10 (13.7) | 0.55 |
Withholding/withdrawal of treatment the day of the study | 105 (12.2) | 41 (9.3) | 47 (13.6) | 17 (23) | 0.002 |