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Table 2 Univariate analysis of risk factors associated with hospital mortality

From: Characteristics and outcome of patients with newly diagnosed advanced or metastatic lung cancer admitted to intensive care units (ICUs)

Variables

Survival patients n = 40 (40%)

Dead patients n = 60 (60%)

p value

Age in years, median [IQR]

63 [52.0–71.0]

65.5 [57.0–73.0]

p = 0.250

Males, n (%)

29 (72.5)

39 (65)

p = 0.560

Days since diagnosis, median [IQR]

4 [0–20.5]

7.5 [0–20.5]

p = 0.460

Histological type, n (%)

  

p = 0.790

 SCLC

12 (30)

18 (30)

 

 NSCLC

28 (70)

42 (70)

 

Metastatic disease, n (%)

23 (57.5)

47 (78)

p = 0.040

Prior chemotherapy, n (%)

7 (17.5)

13 (22)

p = 0.170

Prior radiotherapy, n (%)

3 (7.5)

7 (12)

p = 0.250

ECOG-PS, n (%)

  

p = 0.920

 Low (0–1)

31 (78)

44 (73)

 

 High

9 (22.5)

15 (25)

 

SOFA score, points, median [IQR]

5 [3.5–9.5]

8 [6.0–14.5]

p = 0.010

SAPS II, points, median [IQR]

42.5 [36.5–55.5]

56.5 [46.5–71.0]

p = 0.002

Admission reason, n (%)

  

p = 0.330

 Sepsis

12 (30)

28 (47)

 

 Respiratory (excluding septic reasons)

21 (52.5)

25 (42)

 

 Cardiovascular disease

2 (5)

2 (3)

 

 Neurologic

2 (5)

2 (3)

 

 Post-CPA

0

2 (3)

 

 Other

3 (7.5)

1 (2)

 
  1. IQR interquartile range, SCLC small cell lung cancer, NSCLC non-small cell lung cancer, SOFA Sequential Organ Failure Assessment, SAPS II Simplified Acute Physiology Score, version II, ECOG-PS Eastern Cooperative Oncology Group performance status, CPA cardiopulmonary arrest