Respiratory changes of the inferior vena cava diameter predict fluid responsiveness in spontaneously breathing patients with cardiac arrhythmias

Annals of Intensive Care

Table 3 Accuracy of the inferior vena cava variables for predicting response to volume expansion

Variables	Area under ROC curve [95% CI]	Threshold	Sensitivity [95% CI]	Specificity [95% CI]	Positive predictive value (%)	Negative predictive value (%)
cIVC-st	0.93 [0.86; 1.00]	≥ 39*	0.93 [0.77; 0.99]	0.88 [0.69; 0.97]	89	93
%		≥39	≥0.9		89	93
		≥48		≥0.9	91	84
iIVC-st	0.93 [0.86; 1.00]	< 11*	0.83 [0.64; 0.94]	0.88 [0.69; 0.97]	87	84
mm		<13	≥0.9		76	89
		<9		≥0.9	90	80
eIVC-st	0.77 [0.64; 0.89]	< 19*	0.66 [0.48; 0.83]	0.76 [0.55; 0.91]	73	69
mm		<24	≥0.9		57	82
		<17		≥0.9	92	65
cIVC-sp	0.82 [0.70; 0.93]	≥ 37*	0.66 [0.46; 0.82]	0.85 [0.65; 0.96]	80	70
%		≥11	≥0.9		65	89
		≥43		≥0.9	87	66
iIVC-sp	0.86 [0.76; 0.96]	< 14*	0.79 [0.60; 0.92]	0.81 [0.61; 0.93]	78	82
mm		<20	≥0.9		67	89
		<10		≥0.9	88	69
eIVC-sp	0.83 [0.72; 0.94]	< 18*	0.66 [0.48; 0.83]	0.92 [0.75; 0.99]	90	73
mm		<23	≥0.9		59	83
		<18		≥0.9	90	73

CI confidence interval; IVC inferior vena cava; cIVC-st collapsibility index of the IVC under standardized breathing; iIVC-st minimum-inspiratory diameter of the IVC under standardized breathing; eIVC-st end-expiratory diameter of the IVC under standardized breathing; cIVC-sp collapsibility index of the IVC under unstandardized spontaneous breathing; iIVC-sp minimum-inspiratory diameter of the IVC under unstandardized spontaneous breathing; eIVC-sp end-expiratory diameter of the IVC under unstandardized spontaneous breathing; ROC receiver operating characteristic
*Optimal threshold value to predict response to volume expansion