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Table 2 Respiratory mechanics in early and late prone position according to PEEP strategy

From: Effects of positive end-expiratory pressure strategy in supine and prone position on lung and chest wall mechanics in acute respiratory distress syndrome

Variables Early prone position Late prone position P values
  PEEP/FIO2 table group (n = 19) Pes-guided group (n = 19) PEEP/FIO2 table group (n = 19) Pes-guided group (n = 17) Time effect PEEP strategy effect Time and PEEP interaction
PEEP set on ventilator (cmH2O) 10 ± 2 12 ± 5 10 ± 2 12 ± 4 0.53 0.23 0.50
Paw,ee (cmH2O) 11 ± 3 13 ± 5 11 ± 3 13 ± 4 0.93 0.09 0.26
Paw,ei (cmH2O) 22 ± 4 23 ± 5 22 ± 4 24 ± 4 0.79 0.28 0.67
Pes,ee (cmH2O) 9 ± 4 10 ± 5 9 ± 4 10 ± 6 0.88 0.47 0.07
Pes,ei (cmH2O) 12 ± 5 14 ± 4 12 ± 5 14 ± 5 0.87 0.20 0.07
Pga,ee (cmH2O) 18 ± 5 17 ± 6 17 ± 4 17 ± 5 0.48 0.96 0.77
Pga,ei (cmH2O) 20 ± 5 20 ± 6 19 ± 4 19 ± 6 0.43 0.96 0.75
PL,ee (cmH2O) 2 ± 4 3 ± 1 2 ± 4 3 ± 2 0.82 0.22 0.38
PL,ei (cmH2O) 10 ± 6 9 ± 3 10 ± 5 10 ± 4 0.95 0.69 0.11
PL,ei_Elastance (cmH2O) 16 ± 5 14 ± 5 15 ± 4 14 ± 5 0.96 0.47 0.16
DPrs (cmH2O) 11 ± 4 10 ± 3 11 ± 4 11 ± 4 0.79 0.51 0.17
DPcw (cmH2O) 3 ± 1 4 ± 1 3 ± 1 4 ± 1 0.52 0.02 0.42
DPL (cmH2O) 8 ± 4 6 ± 3 8 ± 4 7 ± 3 0.82 0.19 0.14
Est,rs (cmH2O/L) 34 ± 18 29 ± 11 33 ± 16 30 ± 12 0.76 0.41 0.24
Est,cw (cmH2O/L) 9 ± 3 12 ± 4 9 ± 3 11 ± 5 0.59 0.04 0.37
Est,L (cmH2O/L) 26 ± 18 18 ± 11 24 ± 16 19 ± 10 0.56 0.18 0.12
PaCO2 (mmHg) 50 ± 13 55 ± 13 45 ± 14 48 ± 10 < 0.001 0.42 0.43
PaO2/FIO2 ratio (mmHg) 178 ± 55 193 ± 48 223 ± 85 218 ± 65 < 0.001 0.82 0.27
EELV (mL) 1341 ± 440 1342 ± 445 1504 ± 547 1691 ± 950 0.01 0.63 0.28
  1. Values are mean ± SD
  2. PEEP positive end-expiratory pressure, Paw,ee static end-expiratory pressure of the respiratory system, Paw,ei static end-inspiratory pressure of the respiratory system, Pes,ee static end-expiratory esophageal pressure, Pes,ei static end-inspiratory esophageal pressure, Pga,ee static end-expiratory gastric pressure, Pga,ei static end-inspiratory gastric pressure, PL,ee static end-expiratory transpulmonary pressure, PL,ei static end-inspiratory transpulmonary pressure, PL,ei _Elastance Paw,ei x Est,L/Est,rs, Est,rs, Est,cw, Est,L static elastance, of respiratory system, chest wall and lung, respectively, DPrs, DPcw, DPL driving pressure of respiratory system, chest wall and lung, respectively, EELV end-expiratory lung volume