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Annals of Intensive Care
Fig. 2 | Annals of Intensive Care

Fig. 2

From: Performance of closed-loop resuscitation of haemorrhagic shock with fluid alone or in combination with norepinephrine: an experimental study

Fig. 2

Schematic of the system set-up. The CL-FNE combined a PI regulator for fluid and a FL regulator for NE. Several conditional rules were included to mimic the physician decisions. The algorithm needed three variables: systolic arterial pressure, systolic arterial pressure error and time. During resuscitation, it calculates the ratio of fluid volume/norepinephrine to adapt therapy

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