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Table 1 Characteristics of 60-day survivors and non-survivors of influenza pneumonia-related ARDS before prone positioning

From: Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning

Characteristics

Total patients (n = 65)

Survivors (n = 45)

Non-survivors (n = 20)

p value

Age (years)

57.5 ± 11.8

56.7 ± 13.0

59.3 ± 7.7

0.322

Gender (male/female)

40/25

27/18

13/7

0.702

BMI (kg/m2)

22.4 ± 4.7

27.2 ± 5.1

24.8 ± 3.5

0.057

Severity index

 APACHE II score

24.4 ± 8.7

22.0 ± 8.1

29.8 ± 7.7

0.001*

 SOFA score

11.7 ± 3.6

10.9 ± 3.1

12.9 ± 3.9

0.062

 PSI

115.3 ± 45.0

104.5 ± 38.9

138.4 ± 49.3

0.004*

 CURB-65 score

2.2 ± 1.1

2.2 ± 1.2

2.4 ± 1.0

0.537

Influenza type

   

0.358

 Influenza A

52 (80%)

34 (75.6%)

18 (90.0%)

 

 Influenza B

4 (6%)

3 (6.7%)

1 (5%)

 

 Undetermined

9 (14%)

8 (17.8%)

1 (5%)

 

Laboratory data

 WBC (103/mm3)

9.9 ± 6.7

9.5 ± 6.2

10.9 ± 7.8

0.433

 Lactate (mg/dL)

26.8 ± 29.6

21.9 ± 23.8

36.2 ± 37.4

0.087

 Albumin (g/dL)

3.1 ± 0.5

2.9 ± 0.4

2.7 ± 0.8

0.521

 Creatinine (mg/dL)

1.8 ± 2.3

1.2 ± 0.9

3.1 ± 3.6

0.040*

 Total bilirubin (mg/dL)

0.8 ± 0.7

0.8 ± 0.7

0.7 ± 0.9

0.694

Renal replacement therapy (n, %)

10 (15%)

2 (4.4%)

8 (40.0%)

0.000*

PaCO2 (mm Hg)

48.5 ± 17.6

47.6 ± 19.0

50.7 ± 14.2

0.510

PaO2/FiO2 ratio (mm Hg)

95.9 ± 54.5

102.3 ± 59.8

81.3 ± 37.6

0.153

Tidal volume (ml/kg PBW)

7.7 ± 2.0

7.7 ± 1.9

7.8 ± 2.4

0.985

PEEP (cm H2O)

13.7 ± 3.6

13.5 ± 3.9

14.2 ± 3.0

0.546

Peak airway pressure (cm H2O)

30.7 ± 4.2

31.0 ± 4.5

30.1 ± 3.6

0.468

Dynamic driving pressure (cm H2O)

17.1 ± 4.7

16.9 ± 3.5

16.6 ± 4.2

0.704

Dynamic compliance (ml/cm H2O)

27.1 ± 8.5

26.1 ± 7.9

29.1 ± 9.7

0.200

  1. ARDS acute respiratory distress syndrome, BMI body mass index, APACHE II Acute Physical and Chronic Health Evaluation, SOFA Sequential Organ Function Assessment, PSI pneumonia severity index, CURB-65 CURB-65 for pneumonia severity, WBC white blood cell count, PaCO2 atrial pressure of carbon dioxide in arterial blood, PaO2 atrial pressure of oxygen in arterial blood, FiO2 oxygen fraction in air, PBW predict body weight, PEEP positive end-expiratory pressure
  2. All values are expressed as the number of patients (percentage) or mean ± SD
  3. *p < 0.05: survivors versus non-survivors