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Table 1 Characteristics of 60-day survivors and non-survivors of influenza pneumonia-related ARDS before prone positioning

From: Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning

Characteristics Total patients (n = 65) Survivors (n = 45) Non-survivors (n = 20) p value
Age (years) 57.5 ± 11.8 56.7 ± 13.0 59.3 ± 7.7 0.322
Gender (male/female) 40/25 27/18 13/7 0.702
BMI (kg/m2) 22.4 ± 4.7 27.2 ± 5.1 24.8 ± 3.5 0.057
Severity index
 APACHE II score 24.4 ± 8.7 22.0 ± 8.1 29.8 ± 7.7 0.001*
 SOFA score 11.7 ± 3.6 10.9 ± 3.1 12.9 ± 3.9 0.062
 PSI 115.3 ± 45.0 104.5 ± 38.9 138.4 ± 49.3 0.004*
 CURB-65 score 2.2 ± 1.1 2.2 ± 1.2 2.4 ± 1.0 0.537
Influenza type     0.358
 Influenza A 52 (80%) 34 (75.6%) 18 (90.0%)  
 Influenza B 4 (6%) 3 (6.7%) 1 (5%)  
 Undetermined 9 (14%) 8 (17.8%) 1 (5%)  
Laboratory data
 WBC (103/mm3) 9.9 ± 6.7 9.5 ± 6.2 10.9 ± 7.8 0.433
 Lactate (mg/dL) 26.8 ± 29.6 21.9 ± 23.8 36.2 ± 37.4 0.087
 Albumin (g/dL) 3.1 ± 0.5 2.9 ± 0.4 2.7 ± 0.8 0.521
 Creatinine (mg/dL) 1.8 ± 2.3 1.2 ± 0.9 3.1 ± 3.6 0.040*
 Total bilirubin (mg/dL) 0.8 ± 0.7 0.8 ± 0.7 0.7 ± 0.9 0.694
Renal replacement therapy (n, %) 10 (15%) 2 (4.4%) 8 (40.0%) 0.000*
PaCO2 (mm Hg) 48.5 ± 17.6 47.6 ± 19.0 50.7 ± 14.2 0.510
PaO2/FiO2 ratio (mm Hg) 95.9 ± 54.5 102.3 ± 59.8 81.3 ± 37.6 0.153
Tidal volume (ml/kg PBW) 7.7 ± 2.0 7.7 ± 1.9 7.8 ± 2.4 0.985
PEEP (cm H2O) 13.7 ± 3.6 13.5 ± 3.9 14.2 ± 3.0 0.546
Peak airway pressure (cm H2O) 30.7 ± 4.2 31.0 ± 4.5 30.1 ± 3.6 0.468
Dynamic driving pressure (cm H2O) 17.1 ± 4.7 16.9 ± 3.5 16.6 ± 4.2 0.704
Dynamic compliance (ml/cm H2O) 27.1 ± 8.5 26.1 ± 7.9 29.1 ± 9.7 0.200
  1. ARDS acute respiratory distress syndrome, BMI body mass index, APACHE II Acute Physical and Chronic Health Evaluation, SOFA Sequential Organ Function Assessment, PSI pneumonia severity index, CURB-65 CURB-65 for pneumonia severity, WBC white blood cell count, PaCO2 atrial pressure of carbon dioxide in arterial blood, PaO2 atrial pressure of oxygen in arterial blood, FiO2 oxygen fraction in air, PBW predict body weight, PEEP positive end-expiratory pressure
  2. All values are expressed as the number of patients (percentage) or mean ± SD
  3. *p < 0.05: survivors versus non-survivors